{"paper_id":"49a590da-b63a-4ee2-905f-ff67a1a708fe","body_text":"Endometriosis management after menopause\nDOI:\nhttps://doi.org/10.6016/ZdravVestn.3420Keywords:\nendometriosis, menopause, malignant transformation, oestrogen, menopausal hormone therapyAbstract\nEndometriosis is a disease that can affect 2-5% of all postmenopausal women. It is a disease in which the glands and stroma of the uterus are located outside the maternity area. To date, little is known in the literature about endometriosis in menopausal women. Diagnostic concerns currently relate mainly to concerns about possible malignancy. Reports in the literature describe the recurrence of endometriosis in the postmenopausal period as well as the occurrence of endometriosis de novo. The treatment of choice for symptomatic endometriosis in menopause is the surgical removal of all visible endometriotic tissue, as the risk of recurrence and conversion to malignancy is relatively high. Postmenopausal hormone therapy (MHT) is often used to relieve postmenopausal symptoms and prevent bone loss. There are studies showing that MHZ can reactivate endometriotic foci and even promote malignant transformation of foci in women with a history of endometriosis. Considering the risks of MHZ in patients, which are not fully known, special caution should be exercised with this therapy.\nDownloads\nReferences\n1. Guy JM, Edgar H. Edgar Haydon (1859-1942): general practitioner and radium pioneer. J Med Biogr. 2009;17(3):127-34.\nDOI: 10.1258/jmb.2009.009015\nPMID: 19723958\n2. Janssen EB, Rijkers AC, Hoppenbrouwers K, Meuleman C, D’Hooghe TM. Prevalence of endometriosis diagnosed by laparoscopy in adolescents with dysmenorrhea or chronic pelvic pain: a systematic review. Hum Reprod Update. 2013;19(5):570-82.\nDOI: 10.1093/humupd/dmt016\nPMID: 23727940\n3. Dowlut-McElroy T, Strickland JL. Endometriosis in adolescents. 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Gen Thorac Cardiovasc Surg. 2020;68(12):1584-6.\nDOI: 10.1007/s11748-020-01381-8\nPMID: 32409913\nDownloads\nPublished\nIssue\nSection\nLicense\nThe Author transfers to the Publisher (Slovenian Medical Association) all economic copyrights following form Article 22 of the Slovene Copyright and Related Rights Act (ZASP), including the right of reproduction, the right of distribution, the rental right, the right of public performance, the right of public transmission, the right of public communication by means of phonograms and videograms, the right of public presentation, the right of broadcasting, the right of rebroadcasting, the right of secondary broadcasting, the right of communication to the public, the right of transformation, the right of audiovisual adaptation and all other rights of the author according to ZASP.\nThe aforementioned rights are transferred non-exclusively, for an unlimited number of editions, for the term of the statutory\nThe Author can make use of his work himself or transfer subjective rights to others only after 3 months from date of first publishing in the journal Zdravniški vestnik/Slovenian Medical Journal.\nThe Publisher (Slovenian Medical Association) has the right to transfer the rights of acquired parties without explicit consent of the Author.\nThe Author consents that the Article be published under the Creative Commons BY-NC 4.0 (attribution-non-commercial) or comparable licence.","source_license":"CC0","license_restricted":false}