{"paper_id":"3af5767b-2c68-4293-99e5-6ba827c13798","body_text":"Case Report\nAromatase Inhibitors in the Treatment of Severe Endometriosis\n- Noha A. Mousa\n- Mohamed A. Bedaiwy\n- Robert F. Casper\nBACKGROUND:\nEndometriosis-associated chronic pelvic pain unresponsive to surgical menopause is a difficult clinical problem.\nCASE:\nA middle-aged woman presented with endometriosis and severe pelvic pain after hysterectomy and bilateral salpingo-oopherectomy. She was first treated with exemestane without improvement of symptoms. However, another aromatase inhibitor, letrozole, relieved her pain, and concomitant treatment with estrogen relieved hot flushes without pain reactivation.\nCONCLUSION:\nLetrozole was superior to exemestane in relieving the endometriosis-associated pain in this postmenopausal woman. This suggests that patients may respond variably to different aromatase inhibitors.\nAn aromatase inhibitor relieved persistent endometriosis pain in a posthysterectomy patient.\nCopyright © 2007 by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.","source_license":"CC0","license_restricted":false}