{"paper_id":"33404893-fc69-40d1-b21d-38ceacdfa386","body_text":"Content uploaded by Nazli Ece Gungor\nAuthor content\nAll content in this area was uploaded by Nazli Ece Gungor on Feb 09, 2025\nContent may be subject to copyright.\nTITLE OF PROPOSAL\nThe evaluaon of endometriosis organoid models by using RNAi technology to con!rm the funconal\nbackground of the related genes\nPROBLEM STATEMENT, TOPIC, ISSUE AND RELEVANCE\nPROBLEM STATEMENT: At present, we lack preventave measures, validated screening tools, and\ncurave treatment for endometriosis. Addressing its eology and pathogenesis will enlighten the path\nto supporng the overall well-being of 190 million women worldwide as well as it will minimize the\n!nancial burden on the health care system. Thus, to study the cellular and molecular mechanisms\nrelated to endometrial biology, both appropriate in vivo and in vitro models are indispensable.\nEndometrial organoids (EO), as the name suggests, are self-organizing 3D aggregaons of endometrial\ncells that represent the structure and funcon of the endometrium and give a good model for the\nevaluaon of endometrial diseases such as endometriosis","source_license":"CC0","license_restricted":false}