{"paper_id":"32f837ed-0d8d-4c39-b078-f27d79f862f4","body_text":"Abstract\nSuperovulation with intrauterine insemination (SO-IUI) has been suggested as an alternative to gamete intrafallopian transfer (GIFT), despite the absence of controlled or comparative trials. We retrospectively analyzed all GIFT and SO-IUI cycles performed concurrently from January 1985 to August of 1987 at a single university center. Pregnancy rates were significantly better for GIFT than SO-IUI (P<0.001), with an odds ratio of 3.25 (P=0.001). Stepwise multiple logistic regression identifield factors that correlate with pregnancy: absence of endometriosis (P=0.05), infertility<3 years' duration (P=0.002), TMS ≧30×106 (P=0.005), and treatment with GIFT rather than SO-IUI (P=0.001). These data give a first approximation of the increased efficacy of GIFT versus SO-IUI and provide valuable insight into significant confounding variables to be considered when planning a randomized, prospective trial to evaluate these techniques.\nSimilar content being viewed by others\nReferences\nAsch RH, Ellsworth LR, Balmaceda JP: Pregnancy following translaparoscopic gamete intrafallopian transfer (GIFT). Lancet 1984;2:1034–1035\nMatson PL, Blackledge DG, Richardson PA, Turner SR, Yovich JM, Yovich JL: The role of gamete intrafallopian transfer (GIFT) in the treatment of oligospermic infertility. 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Fertil Steril 1985;44:350–355\nAuthor information\nAuthors and Affiliations\nRights and permissions\nAbout this article\nCite this article\nKaplan, C.R., Olive, D.L., Sabella, V. et al. Gamete intrafallopian transfer vs superovulation with intrauterine insemination for the treatment of infertility. J Assist Reprod Genet 6, 298–304 (1989). https://doi.org/10.1007/BF01139186\nReceived:\nAccepted:\nIssue date:\nDOI: https://doi.org/10.1007/BF01139186","source_license":"public-domain-us","license_restricted":false}