{"paper_id":"319d36ae-3299-4706-b2f0-3f5b1a490fa4","body_text":"Abstract\nMale endometriosis is a rare condition whose exact cause remains elusive, with only a handful of cases (17 cases) documented in literature. In the instances reported previously, endometriotic lesions were frequently observed affixed to the urinary bladder, in the inguinal region, and within the lower abdomen. Proposed explanations for its origin point to a hyper estrogenic environment, possibly linked to prolonged estrogen treatment, cirrhotic liver disease, or chronic surgical inflammation.\nWe report here a rare case of male endometriosis in a 52-year-old diabetic man, who exhibited unusual hematuria and was subsequently diagnosed to have a mass related to the urinary bladder on investigation. Surgical removal and histopathological examination validated the diagnosis. Notably, known etiological factors of male endometriosis were not present in this patient. It is conceivable that persistent embryonic remnants or latent non-alcoholic fatty liver disease in the context of Type II diabetes or obesity may have contributed in the development of endometriosis.\nSimilar content being viewed by others\nReferences\nRock JA, Markham SM (1992) Pathogenesis of endometriosis. Lancet 340:1264–1267\nBontis JN, Vavilis DT (1997) Etiopathology of endometriosis. Ann N Y Acad Sci 816:305–309\nPinkert TC, Catlow CE, Straus R (1979) Endometriosis of the urinary bladder in a man with prostatic carcinoma. Cancer 43:1562–1567\nSimsek G, Bulus H, Tas A, Koklu S, Yilmaz SB, Coskun A (2012) An unusual cause of inguinal hernia in a male patient: Endometriosis. Gut Liver 6:284–285\nFukunaga M (2012) Paratesticular endometriosis in a man with a prolonged hormonal therapy for prostatic carcinoma. Pathol Res Pract 208:59–61\nZamecnik M, Hostakova D (2013) Endometriosis in a mesothelial cyst of tunica vaginalis of the testis: report of a case. Cesk Patol 49(3):134–136\nGonzález RS, Vnencak-Jones CL, Shi C, Fadare O (2014) Endomyometriosis (“Uterus-like mass”) in an XY Male. Int J Surg Pathol 22(5):421–426\nJabr FI, Mani V (2014) An unusual cause of abdominal pain in a male patient: endometriosis. Avicenna J Med 4(4):99–101\nAcknowledgements\nI acknowledge the immense contribution of Dr. Anita Borges, Lab Director & Consultant Pathologist, Centre for Oncopathology, Mumbai, for arriving histopathological diagnosis. Special thanks to Dr. Ranjan Kumar Dey (Urologist) for clinical management.\nAuthor information\nAuthors and Affiliations\nContributions\nAll authors whose names appear on the submission made substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data; or the creation of new software used in the work; drafted the work or revised it critically for important intellectual content; approved the version to be published; and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.\nCorresponding author\nEthics declarations\nInformed Consent\nThe participant has consented to the submission of the case report to the journal.\nConflict of Interest\nThe authors declare no competing interests.\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nRights and permissions\nSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.\nAbout this article\nCite this article\nMandal, A., Tantia, O., Datta, J. et al. Male Endometriosis: Extremely Rare Condition with Unusual Presentation as Haematuria—A Case Report. Indian J Surg 87, 196–199 (2025). https://doi.org/10.1007/s12262-024-04105-x\nReceived:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s12262-024-04105-x","source_license":"CC0","license_restricted":false}