{"paper_id":"2f6b798b-9009-4d4c-9b2f-015afceca914","body_text":"Abstract\nMullerianosis of the urinary bladder is a very rare and morphologically complex tumor-like lesion. It is composed of several types of mullerian-type lesions, including endometriosis, endocervicosis, and endosalpingiosis. This disease occurs in women of the reproductive age group. In the pathogenesis, implantative and metaplastic origins have been suggested, and they are still under discussion. In the present report, a rare case of this lesion in a 41-year-old woman is described. The bladder contained, in addition to typical mullerianosis, glandular cystitis with focal intestinal metaplasia. An interesting and, to our knowledge, hitherto unreported feature was a rare continuity between the glands of mullerianosis and glands of glandular cystitis. The histologic and immunohistochemical findings in the present case support strongly the metaplastic origin of mullerianosis.\nSimilar content being viewed by others\nReferences\nAl-Izzi MS, Horton LWL, Kelleher J, Fawcett D (1994) Malignant transformation in endometriosis of the urinary bladder. Histopathology 14:191–198\nClement PB, Young RH (1992) Endocervicosis of the urinary bladder. Am J Surg Pathol 16:533–542\nDonne C, Vidal M, Buttin X, Becerra P, Carvia R, Zuluaga A, Nogales FF (1998) Mullerianosis of the urinary bladder. Clinical and immunohistochemical findings. Histopathology 33:290–292\nNew NE, Roberts PF (1990) Mucinous metaplasia in endometriosis of the bladder. Histopathology 16:307–308\nOliva E, Amin MB, Jimenez R, Young RH (2002) Clear cell carcinoma of the urinary bladder: a report and comparision of four tumors of mullerian origin and nine of probable urothelial origin with discussion of histogenesis and diagnostic problems. Am J Surg Pathol 26:190–197\nYoung RH, Clement PB (1996) Mullerianosis of the urinary bladder. Mod Pathol 9:731–737\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nKoren, J., Mensikova, J., Mukensnabl, P. et al. Mullerianosis of the urinary bladder: report of a case with suggested metaplastic origin. Virchows Arch 449, 268–271 (2006). https://doi.org/10.1007/s00428-006-0153-1\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00428-006-0153-1","source_license":"CC0","license_restricted":false}