{"paper_id":"28b5eccf-f5e5-4970-9146-cb595db1a9c5","body_text":"Abstract\nEndometriosis is a benign disease characterised by the presence of viable ectopic endometrium outside the uterine cavity. It is commonly found in women of reproductive age. In 1927, Sampson hypothesised that endometriosis develops from retrograde menstruation.1However, retrograde menstruation is common among all menstruating women and during the past decades both a genetic predisposition and immunological dysfunction have been found to be associated with the development of endometriotic lesions.2–5The actual prevalence of endometriosis in women of reproductive age is difficult to ascertain because the diagnosis requires laparoscopy and the indications used for surgery will influence the proportion of patients diagnosed with endometriosis. Furthermore, the prevalence of endometriosis seems to be geographically different. One possible explanation might be exposure to irradiation, polychlorinated biphenyls or dioxin.6,7\nPreview\nUnable to display preview. Download preview PDF.\nSimilar content being viewed by others\nReferences\nSampson JA (1927) Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol 14:422–469\nMalinak LR Buttram VC Jr Elias S et al(1980)Heritage aspects of endometriosis. II. Clinical characteristics of familial endometriosis. Am J Obstet Gynecol 137:332–337\nDmowski WP, Steele RW, Baker GF et al. (1981) Deficient cellular immunity in endometriosis. Am J Obstet Gynecol 141:377–383\nOosterlynck D, Cornillie FJ:, Waer M et al. (1991) Women with endometriosis show a defect in natural killer cell activity resulting in a decreased cytotoxicity to autologous endometrium. Fertil Steril 56:45–51\nVercellini P, Sacerdote P, Panerai AE et al. 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Springer, London. https://doi.org/10.1007/978-1-4471-0655-5_26\nDownload citation\nDOI: https://doi.org/10.1007/978-1-4471-0655-5_26\nPublisher Name: Springer, London\nPrint ISBN: 978-1-4471-1170-2\nOnline ISBN: 978-1-4471-0655-5\neBook Packages: Springer Book Archive\nKeywords\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}