{"paper_id":"288e8465-1938-4532-acb4-3e0d32caf928","body_text":"Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.\nThe relationship between uterine prolapse and premalignant endometrial pathology\nAffiliations\nArticle Info\n1 Department of Obstetrics and Gynecology, Sifa University School of Medicine, İzmir\n2 Department of Obstetrics and Gynecology, Celal Bayar University School of Medicine, Manisa\n3 Department of Obstetrics and Gynecology, Eagean Maternity and Women’s Health Training Hospital, İzmir (Turkey)\nAbstract\nObjective: The aim of this study was to stress the importance of performing a thorough uterine assessment before selecting an organsparing surgery in patients presenting with uterine prolapse and no other complaints. Materials and Methods: This study included a total of 111 participants who presented with pelvic organ prolapse and underwent hysterectomy for grades 3-4 uterine prolapse. The posthysterectomy histopathology results were classified as benign (atrophic endometrium, proliferative or secretory endometrium) or pathologic (endometrial hyperplasia, endometrial polyp, adenomyosis, myoma uteri, and endometrium carcinoma). Results: Of the 111 patients enrolled in this study, 23 (20.2%) had endometrial hyperplasia, eight (7.2%) had endometrial polyps, 30 (27%) had uterine fibroids, and 20 (18%) had adenomyosis. Conclusion: There may be premalignant lesions of the endometrium in both premenopausal and postmenopausal women presenting with uterine prolapse and no other symptoms. A chronic inflammatory process resulting from the extra-vaginal location of the uterus may play a role in the development of these lesions. Further studies are needed on this subject.\nKeywords\n- Uterine prolapse\n- Hysterectomy\n- Endometrial hyperplasia","source_license":"CC0","license_restricted":false}