{"paper_id":"28526202-66b3-476a-a2fb-79e90e336932","body_text":"Abstract\nMagnetic resonance imaging (MRI) is recommended to be used as a second-line diagnostic modality for adenomyosis in cases when transvaginal ultrasound does not provide sufficient diagnostic certainty. The strengths of MRI are high resolution and low susceptibility to artifacts, for example, in the presence of large fibroids. However, to achieve optimal results and diagnostic reliability, technical requirements need to be met, and expertise in diagnosing adenomyosis is needed. High-intensity signal spots, cysts, and indentations at the endometrial-myometrial junction and diffusely demarcated low-intensity signal areas in T2-weighted (T2W) sequences are the most commonly found diagnostic markers of adenomyosis in MRI. Hemorrhagic components can be identified in T1W sequences.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nReferences\nTellum T, Nygaard S, Lieng M. Noninvasive diagnosis of adenomyosis: a structured review and meta-analysis of diagnostic accuracy in imaging. J Minim Invasive Gynecol. 2020;27(2):408–18.\nChapron C, Vannuccini S, Santulli P, Abrão MS, Carmona F, Fraser IS, et al. Diagnosing adenomyosis: an integrated clinical and imaging approach. Hum Reprod Update. 2020;26(3):392–411.\nMcGee S. Simplifying likelihood ratios. J Gen Intern Med. 2002;17(8):646–9.\nNaftalin J, Hoo W, Nunes N, Holland T, Mavrelos D, Jurkovic D. Association between ultrasound features of adenomyosis and severity of menstrual pain. Ultrasound Obstet Gynecol. 2016;47(6):779–83.\nMitchell DG, Schonholz L, Hilpert PL, Pennell RG, Blum L, Rifkin MD. Zones of the uterus: discrepancy between US and MR images. Radiology. 1990;174(3 Pt 1):827–31.\nTurnbull LW, Manton DJ, Horsman A, Killick SR. Magnetic resonance imaging changes in uterine zonal anatomy during a conception cycle. Br J Obstet Gynaecol. 1995;102(4):330–1.\nBazot M, Darai E. Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis. Fertil Steril. 2018;109(3):389–97.\nTamai K, Togashi K, Ito T, Morisawa N, Fujiwara T, Koyama T. MR imaging findings of adenomyosis: correlation with histopathologic features and diagnostic pitfalls. Radiographics. 2005;25(1):21–40.\nBazot M, Cortez A, Darai E, Rouger J, Chopier J, Antoine JM, et al. Ultrasonography compared with magnetic resonance imaging for the diagnosis of adenomyosis: correlation with histopathology. Hum Reprod (Oxf, Engl). 2001;16(11):2427–33.\nDueholm M, Lundorf E, Hansen ES, Sorensen JS, Ledertoug S, Olesen F. Magnetic resonance imaging and transvaginal ultrasonography for the diagnosis of adenomyosis. Fertil Steril. 2001;76(3):588–94.\nTellum T, Matic GV, Dormagen JB, Nygaard S, Viktil E, Qvigstad E, et al. Diagnosing adenomyosis with MRI: a prospective study revisiting the junctional zone thickness cutoff of 12 mm as a diagnostic marker. Eur Radiol. 2019;29(12):6971–81.\nMunro MG. Classification and reporting systems for adenomyosis. J Minim Invasive Gynecol. 2020;27(2):296–308.\nGordts S, Campo R, Brosens I. Hysteroscopic diagnosis and excision of myometrial cystic adenomyosis. Gynecol Surg. 2014;11(4):273–8.\nPontrelli G, Bounous VE, Scarperi S, Minelli L, Di Spiezio Sardo A, Florio P. Rare case of giant cystic adenomyoma mimicking a uterine malformation, diagnosed and treated by hysteroscopy. J Obstet Gynaecol Res. 2015;41(8):1300–4.\nBrosens I, Gordts S, Habiba M, Benagiano G. Uterine cystic adenomyosis: a disease of younger women. J Pediatr Adolesc Gynecol. 2015;28(6):420–6.\nNaftalin J, Bean E, Saridogan E, Barton-Smith P, Arora R, Jurkovic D. Imaging in gynecological disease: clinical and ultrasound characteristics of accessory cavitated uterine malformations. Ultrasound Obstet Gynecol. 2021;57(5):821–8.\nReinhold C, Tafazoli F, Mehio A, Wang L, Atri M, Siegelman ES, et al. Uterine adenomyosis: endovaginal US and MR imaging features with histopathologic correlation. Radiographics. 1999;19 Spec No:S147–60.\nTamai K, Koyama T, Umeoka S, Saga T, Fujii S, Togashi K. Spectrum of MR features in adenomyosis. Best Pract Res Clin Obstet Gynaecol. 2006;20(4):583–602.\nLee JK, Gersell DJ, Balfe DM, Worthington JL, Picus D, Gapp G. The uterus: in vitro MR-anatomic correlation of normal and abnormal specimens. Radiology. 1985;157(1):175–9.\nDemas BE, Hricak H, Jaffe RB. Uterine MR imaging: effects of hormonal stimulation. Radiology. 1986;159(1):123–6.\nBrown HK, Stoll BS, Nicosia SV, Fiorica JV, Hambley PS, Clarke LP, et al. Uterine junctional zone: correlation between histologic findings and MR imaging. Radiology. 1991;179(2):409–13.\nReinhold C, McCarthy S, Bret PM, Mehio A, Atri M, Zakarian R, et al. Diffuse adenomyosis: comparison of endovaginal US and MR imaging with histopathologic correlation. Radiology. 1996;199(1):151–8.\nByun JY, Kim SE, Choi BG, Ko GY, Jung SE, Choi KH. Diffuse and focal adenomyosis: MR imaging findings. Radiographics. 1999;19 Spec No:S161–70.\nSong SE, Sung DJ, Park BJ, Kim MJ, Cho SB, Kim KA. MR imaging features of uterine adenomyomas. Abdom Imaging. 2011;36(4):483–8.\nBazot M, Darai E, Clement de Givry S, Boudghene F, Uzan S, Le Blanche AF. Fast breath-hold T2-weighted MR imaging reduces interobserver variability in the diagnosis of adenomyosis. AJR Am J Roentgenol. 2003;180(5):1291–6.\nAgostinho L, Cruz R, Osorio F, Alves J, Setubal A, Guerra A. MRI for adenomyosis: a pictorial review. Insights Imaging. 2017;8(6):549–56.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG\nAbout this chapter\nCite this chapter\nTellum, T. (2022). Noninvasive Diagnosis of Adenomyosis: Magnetic Resonance Imaging (MRI). In: Oral, E. (eds) Endometriosis and Adenomyosis. Springer, Cham. https://doi.org/10.1007/978-3-030-97236-3_34\nDownload citation\nDOI: https://doi.org/10.1007/978-3-030-97236-3_34\nPublished:\nPublisher Name: Springer, Cham\nPrint ISBN: 978-3-030-97235-6\nOnline ISBN: 978-3-030-97236-3\neBook Packages: MedicineMedicine (R0)","source_license":"CC0","license_restricted":false}