{"paper_id":"270556e5-b0eb-4f28-8597-a2bd37326ade","body_text":"Abstract\nBackground\nEndometriosis-associated ovarian cancer arising from the surgical incision site is an unusual clinical entity.\nCase\nA 37-year-old woman presented with a chief complaint of progressive swelling of the mons pubis. The patient was status post laparotomy for endometrioma/endometriosis 10 years ago. MRI showed a heterogeneous multiseptated large cystic mass within the mons pubis measuring 14 × 13.4 × 10.6 cm. Initial cytoreductive surgery revealed no evidence of tumor in the peritoneal cavity. The surgery was suboptimal due to severe adhesions to the symphysis pubis. The secondary cytoreductive surgery performed after six cycles of taxotere and carboplatin was optimal. Macroscopically, the tumor was a dusky pink-purple and contained a dense white-gray to light yellow gelatinous area. The tumor was a malignant cystic and glandular neoplasm. Immunohistochemical stains included CK7(+), CK5/6(−), EMA(+), Ber-Ep4(+), Calretinin(−), ER(−), and PR(−).\nConclusion\nPrimary peritoneal clear cell adenocarcinoma arising from an abdominal scar associated with prior endometrioma/endometriosis surgery was first reported.\nReferences\nSomigliana E, Vigano’ P, Parazzini F, Stoppelli S, Giambattista E, Vercellini P (2006) Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence. Gynecol Oncol 101:331–341. doi:10.1016/j.ygyno.2005.11.033\nModesitt SC, Tortolero-Luna G, Robinson JB, Gershenson DM, Wolf JK (2002) Ovarian and extraovarian endometriosis-associated cancer. Obstet Gynecol 100:788–795. doi:10.1016/S0029-7844(02)02149-X\nMatthes G, Zabel DD, Nastala CL, Shestak KC (1998) Endometrioma of the abdominal wall following combined abdominoplasty and hysterectomy: case report and review of the literature. Ann Plast Surg 40:672–675. doi:10.1097/00000637-199806000-00019\nMajeski J, Craggie J (2004) Scar endometriosis developing after an umbilical hernia repair with mesh. South Med J 97:532–534. doi:10.1097/00007611-200405000-00024\nGunes M, Kayikcioglu F, Ozturkoglu E, Haberal A (2005) Incisional endometriosis after cesarean section, episiotomy and other gynecologic procedures. J Obstet Gynaecol Res 31:471–475. doi:10.1111/j.1447-0756.2005.00322.x\nHealy JT, Wilkinson NW, Sawyer M (1995) Abdominal wall endometrioma in a laparoscopic trocar tract: a case report. Am Surg 61:962–963\nLeng J, Lang J, Guo L, Li H, Liu Z (2006) Carcinosarcoma arising from atypical endometriosis in a cesarean section scar. Int J Gynecol Cancer 16:432–435. doi:10.1111/j.1525-1438.2006.00199.x\nMadsen H, Hansen P, Andersen OP (1980) Endometrioid carcinoma in an operation scar. Acta Obstet Gynecol Scand 59:475–476\nLee KR, Verma U, Belinson J (1991) Primary clear cell carcinoma of the peritoneum. Gynecol Oncol 41:259–262. doi:10.1016/0090-8258(91)90320-5\nTerada T, Kawaguchi M (2005) Primary clear cell adenocarcinoma of the peritoneum. Tohoku J Exp Med 206:271–275. doi:10.1620/tjem.206.271\nDincer AD, Timmins P, Pietrocola D, Fisher H, Ambros RA (2002) Primary peritoneal mullerian adenosarcoma with sarcomatous overgrowth associated with endometriosis: a case report. Int J Gynecol Pathol 21:65–68. doi:10.1097/00004347-200201000-00012\nSampson JA (1980) Endometrial carcinoma of the ovary, arising in endometrial tissue in that organ. Arch Surg 10:1–72. http://archsurg.ama-assn.org/content/vol10/issue1/index.dtl\nMostoufizadeh M, Scully RE (1980) Malignant tumors arising in endometriosis. Clin Obstet Gynecol 23:951–963. doi:10.1097/00003081-198023030-00024\nRust MM, Susa J, Naylor R, Cavuoti D (2008) Clear cell carcinoma in a background of endometriosis. Case report of a finding in a midline abdominal scar 5 years after a total abdominal hysterectomy. Acta Cytol 52:475–480\nConflict of interest statement\nNone.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nMatsuo, K., Alonsozana, E.L.C., Eno, M.L. et al. Primary peritoneal clear cell adenocarcinoma arising in previous abdominal scar for endometriosis surgery. Arch Gynecol Obstet 280, 637–641 (2009). https://doi.org/10.1007/s00404-009-0962-y\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s00404-009-0962-y","source_license":"CC0","license_restricted":false}