{"paper_id":"2277a174-e766-4568-8d76-702b5c4b905e","body_text":"Abstract\nEndometriosis (EM), a refractory, highly recurrent and life-threatening chronic disease, requires long-term management and long-term drug treatment. Our previous studies showed that Chinese medicine (CM) can inhibit the postoperative recurrence of EM, improve quality of life, shorten the time to conception and increase pregnancy rates. CM produces few adverse reactions with high safety. These characteristics might be associated with the mechanism of CM’s inhibition of recurrence. Therefore, we believe that CM may represent a good choice for long-term drug treatment and is worthy of clinical application.\nSimilar content being viewed by others\nReferences\nLeng JH, Dai Y. New ideas for the treatment of endometriosis. Chin J Obstet Gynecol (Chin) 2017;52:433–435.\nLang JH. The study and hypothesis of endometriosis. Chin J Obstet Gynecol (Chin) 2003;38:478–480.\nLiu SJ, Zhang W, Zhang XH, Cai GQ, Zhou W, et al. The implementation of de-escalation therapy for inhibition and protection of ovarian function in lifetime management of endometriosis. Med Phil (Chin) 2015;36:22–25.\nRothenberg RB, Koplan JP. Chronic disease in the 1990s. Annu Rev Public Health 1990;11:267–296.\nLu M, Cui YM, Bai WP. Pharmaceutical care model on chronic disease management. Chin J New Drugs (Chin) 2014;23:244–246.\nLi TT, Sun WW, Zhao RH. Clinical observation on the treatment with Huoxue Xiaoyi Fang for ovarian endometriosis with syndrome of qi stagnation and blood stasis. Modern J Integr Tradit West Med (Chin) 2018;27:484–487, 549.\nCui YY, Sun WW, Zhao RH. Systematic review of Chinese herbal medicine for controlling recurrence of endometriosis after operation. J Shandong Univ Tradit Chin Med (Chin) 2014;38:529–533.\nZhao RH, Hao ZP, Zhang Y, Lian FM, Sun WW, Liu Y, et al. Controlling the recurrence of pelvic endometriosis after a conservative operation: comparison between Chinese herbal medicine and Western medicine. Chin J Integr Med 2013;19:820–825.\nZhao RH, Liu Y, Tan Y, Hao ZP, Meng QW, Wang R, et al. Chinese medicine improves postoperative quality of life in endometriosis patients: a randomized controlled trial. Chin J Integr Med 2013;19:15–21.\nPractice Committee of the American Society for Reproductive Medicine. Treatment of pelvic pain associated with endometriosis: a committee opinion. Fertil Steril 2014;101:927–935.\nLiang JH, ed. A Meta of clinical guide collected by Chinese Journal of Obstetrics and Gynecology (2015 ed). Beijing: People’s Medical Publishing House;2015:311.\nKvaskof M, Mu F, Tery K L, Harris HR, Poole EM, Farland L, et al. Endometriosis: a high-risk population for major chronic diseases. Hum Reprod Update 2015;21:500–516.\nZhang W, Chen LF, Liu SJ, Yang H, Xin XY. Practice the basic principle of \"patient benefit\": a discussion from the clinical management of endometriosis involving the urinary and reproductive system. Med Phil 2014;35:81–83.\nKuznetsov L, Dworzynski K, Davies M. Diagnosis and management of endometriosis: summary of NICE guidance. BMJ 2017;358:j3935\nLi MH, Leng JH, Li CL, Shi JH, Jia SZ, Lang JH. Study on the expression of tPA and PAI-1 in endometriosis peritoneum treated by GnRH-a. Prog Obstet Gynecol 2012;21:20–23.\nWu XY, Wan ZQ, Zhang YZ. Zoladex combined with Laparoscopic surgery to treat 38 cases of endometriosis. Zhejiang J Prev Med (Chin) 2006;18:45–47.\nGuo SW. Recurrence of endometriosis and its control. Hum Reprod Update 2009;15:441–461.\nJee BC, Lee JY, Suh CS. Impact of GnRH agonist treatment on recurrence of ovarian endometriomas after conservative laparoscopic surgery. Fertil Steril 2009;91:40–45.\nYang LB. Long-term management of endometriosis. Modern Med Health 2017;1:156–158.\nZhao RH, Yang YH, Li M, Xu C, Xia WY. Influences of Huoxue Xiaoyi Fang on ICAM-1, MMP-9 and VEGF in rats with endometriosis. J Beijing Univ Chin Med (Chin) 2012;35:826–830.\nSun WW, Yang YH, Hao ZP, Li M, Zheng Y. Effect of Danchi Decoction on serum interleukin of endometriosis. Chin J Inf Tradit Chin Med (Chin) 2014;21:14–17.\nYang YH, Zhao RH, Hao ZP, Li L, Xu C. Effects of Danchi Decoction on P450arom, survivin of eutopic endometrium of patients with endometriosis after conservative surgery. Afr J Tradit Complement Altern Med 2015;12:65–71.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nZhao, Rh., Sun, Ww., Liu, Y. et al. Chinese Medicine in Management of Chronic Disease Endometriosis. Chin. J. Integr. Med. 26, 88–91 (2020). https://doi.org/10.1007/s11655-018-2937-3\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s11655-018-2937-3","source_license":"CC0","license_restricted":false}