{"paper_id":"2066cf57-4e49-4405-beb6-6912986807d9","body_text":"Abstract\nUndisturbed LH action is essential for normal follicular maturation, ovulation and corpus luteum formation. In polycystic ovarian disease (PCOD), pituitary LH secretion, at least in relation to FSH secretion, is pathologically high1. There are also diseases, e.g. endometriosis2, known often to be accompanied by unexplained infertility in spite of apparently normal concentrations of circulating gonadotrophins. In such conditions the follicular membrane receptors mediating the action of LH might be at fault. For these reasons we measured the LH(hcG) receptor concentrations of the Graafian follicle or the corpus luteum cells of patients suffering from PCOD or endometriosis.\nPreview\nUnable to display preview. Download preview PDF.\nSimilar content being viewed by others\nReferences\nSpellacy, W. N. (1981). Polycystic ovarian disease. Fertil. Steril., 36, 306\nDmowski, W. P. (1981). Current concepts in the management of endometriosis. Obstet. Gynecol. Ann., 10, 279\nRajaniemi, H., Rönnberg, L., Kauppila, A., Ylöstalo, P. and Vihko, R. (1980). Luteinizing hormone receptors in ovarian follicles of patients with polycystic ovarian disease. J. Clin. Endocrinol. Metab., 51, 1054\nKauppila, A., Rajaniemi, H. and Rönnberg, L. (1982), Low LH(hCG) receptor concentration in ovarian follicles in endometriosis. Acta Obstet. Gynecol. Scand., 61, 81\nRönnberg, L., Kauppila, A. and Rajaniemi, H. (1984). LH(hCG) receptor disorder in endometriosis. Fertil. Steril. (In press)\nRao, Ch.V. (1982). Receptors for gonadotropins in human ovaries. In Recent Advances in Fertility Research. Part A: Developments in Reproductive Endocrinology. pp. 123–35. ( New York: Alan R. Liss )\nCopman, T. L. and Adams, W. C. (1981). Ovarian gonadotropin receptor during experimental ovarian cyst formation in the rat. Biol. Reprod., 25, 115\nMuse, K., Wilson, E. A. and Jawad, M. J. (1982). Prolactin hyperstimulation in response to thyrotropin-releasing hormone in patients with endometriosis. Fertil. Steril., 38, 542\nMcNeilly, A. S. (1980). Paradoxical prolactin. Nature (Lond.), 284, 212\nKauppila, A., Leinonen, P., Vihko, R. and Ylöstalo, P. (1982). Metoclopramide-induced hyperprolactinaemia impairs ovarian follicle maturation and corpus luteum formation in women. J. Clin. Endocrinol. Metab., 54, 955\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 1984 MTP Press Limited\nAbout this chapter\nCite this chapter\nKauppila, A., Rajaniemi, H., Rönnberg, L. (1984). Decreased concentration of ovarian LH(hCG) receptor in polycystic ovarian disease and endometriosis. In: Harrison, R.F., Bonnar, J., Thompson, W. (eds) Diagnosis and Management of Tubo-Uterine Factors in Infertility. Studies in Fertility and Sterility, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-7621-7_19\nDownload citation\nDOI: https://doi.org/10.1007/978-94-011-7621-7_19\nPublisher Name: Springer, Dordrecht\nPrint ISBN: 978-94-011-7623-1\nOnline ISBN: 978-94-011-7621-7\neBook Packages: Springer Book Archive\nKeywords\n- Corpus Luteum\n- Ovarian Follicle\n- Luteinizing Hormone Receptor\n- Receptor Concentration\n- Unexplained Infertility\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}