{"paper_id":"1ecea810-b16a-4598-acc6-9f1e0697f388","body_text":"Back to Journals » Stem Cells and Cloning: Advances and Applications » Volume 1\nRegeneration and adult stem cells in the human female reproductive tract\nAuthors Ono M, Maruyama T, Yoshimura Y\nPublished 2 December 2008 Volume 2008:1 Pages 23—29\nDOI https://doi.org/10.2147/SCCAA.S4269\nReview by Single anonymous peer review\nPeer reviewer comments 2\nMasanori Ono, Tetsuo Maruyama, Yasunori Yoshimura\nDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku, Tokyo, Japan\nAbstract: The human uterus is unique in that it exhibits a tremendous regenerative capacity that enables cyclical regeneration and remodeling throughout a woman’s reproductive life. This plasticity of the reproductive system has recently been highlighted. Regeneration and remodeling in the female reproductive tract alludes to the existence of endometrial and myometrial stem cell systems, which has been supported by increasing experimental evidence. Characterization of these stem cells, along with the study of the mechanisms controlling their regeneration, will improve the understanding of the physiology and pathophysiology of the female reproductive tract.\nKeywords: adult stem cells, endometrium, myometrium, regeneration\n© 2008 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms and incorporate the Creative Commons Attribution - Non Commercial (unported, 3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.","source_license":"CC0","license_restricted":false}