{"paper_id":"190082ec-1266-4ff6-bd0a-bece377ad2ba","body_text":"Subscribe to RSS\nDOI: 10.1055/s-0042-1756235\nMagnetic Resonance-Guided High-Intensity Focused Ultrasound Treatment of Uterine Fibroids: The First Egyptian Experience\nAuthors\nIntroduction: Uterine fibroids are benign encapsulated uterine tumors that disrupt the functions of the uterus causing many symptoms ranging from menorrhagia and dysmenorrhea to recurrent pregnancy loss, and infertility, and are the most common reason for hysterectomy in premenopausal women. Magnetic resonance imaging (MRI)-guided high-intensity focused ultrasound (MR-HIFU) is a recent very low-pain to painless noninvasive procedure that has shown excellent therapeutic efficacy in treating uterine fibroids. Here, we present the MRI findings of the first cohort of Egyptian women with uterine fibroids who underwent MR-HIFU.\nMaterials and Methods: Twenty Egyptian female patients in their reproductive age (18–45 years) with a total of 30 symptomatic uterine fibroids measuring between 3 and 12 cm in diameter underwent MR-HIFU treatment in the National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt over a period of 9 months (Feb 2021–Dec 2021). Fibroid size, T1 and T2 signal intensities, and Funaki type and nonperfused volume of uterine fibroids were recorded pre- and/or posttreatment. The mean fibroid volume change after 6 months was also noted. Also, symptom relief was recorded.\nResult: Remarkably, all 30 fibroids showed no less than 70% nonperfused volume in the contrast-enhanced MRI performed directly after the session. Follow-up showed significant relief in the primary symptoms mainly bleeding and significant improvement in Hemoglobin level and also follow-up size reduction was measured and showed at least 30% decrease in size.\nConclusions: Our institution is the first to introduce the ground-breaking technology of MR-HIFU in Egypt. We have shown high efficacy of MR-HIFU in the treatment of uterine fibroids in Egyptian women. Our results have great potential of the wider use of this minimally invasive and effective treatment of uterine fibroids not just in Egypt but all the Middle East and Africa.\nPublication History\nArticle published online:\n17 August 2022\n© 2022. The Pan Arab Interventional Radiology Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)\nThieme Medical and Scientific Publishers Pvt. Ltd.\nA-12, 2nd Floor, Sector 2, Noida-201301 UP, India","source_license":"CC0","license_restricted":false}