{"paper_id":"187a23a9-4620-4a9b-a308-3efd6c919cbe","body_text":"Abstract\nDisorders of menstruation present a significant burden to health services. Furthermore, hysterectomy, the definitive surgical treatment for menorrhagia, is the most common major operation performed on women of reproductive age in Britain and America [1–3]. Heavy menstrual bleeding may be the result of organic disease such as fibroids, infection or malignancy, but in most cases, no such underlying lesion can be found and the diagnosis of dysfunctional bleeding is made. In some circumstances, and especially at the extremes of the reproductive career, dysfunctional bleeding may be the result of anovulation [4,5]. However, in most women with regular but heavy periods no abnormality of the hypothala-mopituitary axis can be demonstrated, and the abnormality is therefore thought to lie at the level of the endometrium itself [6].\nPreview\nUnable to display preview. 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J Reprod Fertil 1991; 91:301–12.\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 1992 Royal College of Obstetricians and Gynaecologists\nAbout this chapter\nCite this chapter\nCameron, I.T. (1992). Prostaglandins and Menstruation. In: Drife, J.O., Calder, A.A. (eds) Prostaglandins and the Uterus. Springer, London. https://doi.org/10.1007/978-1-4471-1931-9_2\nDownload citation\nDOI: https://doi.org/10.1007/978-1-4471-1931-9_2\nPublisher Name: Springer, London\nPrint ISBN: 978-1-4471-1933-3\nOnline ISBN: 978-1-4471-1931-9\neBook Packages: Springer Book Archive\nKeywords\n- Okadaic Acid\n- Human Endometrium\n- Heavy Menstrual Bleeding\n- Menstrual Blood Loss\n- Dysfunctional Uterine Bleeding\nThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.","source_license":"CC0","license_restricted":false}