{"paper_id":"0ed38c78-87eb-40a9-92e2-c168be2dbe33","body_text":"Abstract\nEndometriosis, a chronic and multifocal inflammatory condition with a substantial estrogen-dependent component, is often linked to infertility. Some patients with endometriosis may require surgical intervention or assisted reproductive technologies to conceive. Although many patients who achieve pregnancy have relatively uncomplicated outcomes because of the progesterone-induced regression of endometriotic lesions, complications can still arise during pregnancy and the peripartum period. Complications include the decidualization of endometriosis implants, with site-specific implications (e.g., decidualized endometrioma mimicking ovarian cancer, decidualized deep endometriosis infiltrating the myometrium leading to uterine rupture, spontaneous hemoperitoneum), placenta previa, preterm labor and premature rupture of membranes, postpartum hemorrhage, or systemic conditions such as hypertensive or coagulation disorders. Herein, we review the background of these conditions and the expected radiologic findings. Additionally, we review essential clinical concepts about the treatment available and the information needed to make health care decisions. This review aims to equip radiologists with essential insights into the challenges faced by patients with endometriosis, from infertility diagnosis through postpartum care. By enhancing radiologists’ understanding of these aspects and relevant imaging findings, we aspire to improve maternal and fetal outcomes affected by this complex condition.\nSimilar content being viewed by others\nData Availability\nNo datasets were generated or analysed during the current study.\nReferences\nVercellini P, Viganò P, Bandini V, Buggio L, Berlanda N, Somigliana E. Association of endometriosis and adenomyosis with pregnancy and infertility. Fertil Steril 2023;119(5):727-740. https://doi.org/10.1016/j.fertnstert.2023.03.018\nBallard K, Lowton K, Wright J. What's the delay? A qualitative study of women's experiences of reaching a diagnosis of endometriosis. Fertil Steril 2006;86(5):1296-1301. https://doi.org/10.1016/j.fertnstert.2006.04.054\nEndometriosis and infertility: a committee opinion. Fertil Steril 2012;98(3):591-598. https://doi.org/10.1016/j.fertnstert.2012.05.031\nBalasch J, Creus M, Fábregues F, Carmona F, Ordi J, Martinez-Román S, Vanrell JA. 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LC,KB,MB,ZK, JL, WVB, LI reviewed the article and figures All authors reviewed the final content submitted for consideration.\nCorresponding author\nEthics declarations\nConflict of interest\nThe authors declare no competing interests.\nAdditional information\nPublisher's Note\nSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.\nSupplementary Information\nBelow is the link to the electronic supplementary material.\nSupplementary file1 (MP4 5591 KB)\nSupplementary file2 (MP4 3498 KB)\nSupplementary file3 (MP4 2446 KB)\nRights and permissions\nSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.\nAbout this article\nCite this article\nCausa Andrieu, P., Stewart, K., Chun, R. et al. Endometriosis: a journey from infertility to fertility. Abdom Radiol 50, 5405–5421 (2025). https://doi.org/10.1007/s00261-025-04935-7\nReceived:\nRevised:\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s00261-025-04935-7","source_license":"CC0","license_restricted":false}