{"paper_id":"0ae0f39f-93a6-4ce4-97d9-2771a6a986f0","body_text":"Abstract\nWith the advancement of imaging technology, such as ultrasound, more and more patients with asymptomatic adenomyosis are diagnosed, so the incidence of adenomyosis is higher than traditionally thought [1]. An epidemiological study from healthcare institutes in Italy had found that the incidence of adenomyosis in women of reproductive age was 0.02–0.03%, and the prevalence was 0.17% [2]. A cohort study in the United States observed 330,000 women for 10 years and found that the total incidence of adenomyosis in women aged 16–60 years was 1%. The study also found that black women had the highest incidence, while Asian women had the lowest incidence, and white women were somewhere in between [3]. From the literature, there were wide variations in the incidence and prevalence of adenomyosis, and it might be due to the difficulties in accurately assessing the incidence [4–6]. Firstly, there was selection bias in women with indications for a hysterectomy or surgery when this disease was being diagnosed. Secondly, there was a lack of consensus of histological criteria to diagnose adenomyosis, raising concerns about the reproducibility of its histological diagnosis. Thirdly, the increasing use of MRI or ultrasound imaging on symptomatic patients to diagnose this disease without histological confirmation contributed to the increasing incidence in the general population. Nevertheless, the incidence of adenomyosis is related to the patient’s age, the number of pregnancy, and pelvic endometriosis.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nReferences\nPeric H, Fraser I. The symptomatology of adenomyosis. Best Pract Res Clin Obstet Gynaecol. 2006;20(4):547–55.\nMorassutto C, et al. Incidence and estimated prevalence of endometriosis and adenomyosis in Northeast Italy: a data linkage study. PLoS One. 2016;11(4)\nOnchee Y, et al. Adenomyosis incidence, prevalence and treatment: United States population – based study 2006–2015. Am J Obstet Gynecol. 2020;223(1):94.e1–94.e10.\nChrysostomou M, et al. Incidence of adenomyosis uteri in a Greek population. Acta obstetricia et gynecologica Scandinavica. 1991;70(6):441–4.\nRaju GC, et al. Adenomyosis uteri: a study of 416 cases. Aust N Z J Obstet Gynaecol. 1988;28(1):72–3.\nBird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterus—revisited. Am J Obstet Gynecol. 1972;112(5):583–93.\nNaftalin J, et al. How common is adenomyosis? A prospective study of prevalence using transvaginal ultrasound in a gynaecology clinic. Hum Reprod. 2012;27(12):3432–9.\nGordts S, Grimbizis G, Campo R. Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis. Fertil Steril. 2018;109(3):380–388.e1.\nHarada T, et al. The impact of adenomyosis on women’s fertility. Obstet Gynecol Surv. 2016;71(9):557.\nAuthor information\nAuthors and Affiliations\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.\nAbout this chapter\nCite this chapter\nFan, Z. (2021). The Incidence and Clinical Impact of Adenomyosis. In: Xue, M., Leng, J., Wong, F. (eds) Adenomyosis. Springer, Singapore. https://doi.org/10.1007/978-981-33-4095-4_1\nDownload citation\nDOI: https://doi.org/10.1007/978-981-33-4095-4_1\nPublished:\nPublisher Name: Springer, Singapore\nPrint ISBN: 978-981-33-4094-7\nOnline ISBN: 978-981-33-4095-4\neBook Packages: MedicineMedicine (R0)","source_license":"CC0","license_restricted":false}