{"paper_id":"0935cfdd-69ea-4366-8c7a-4c153199ec61","body_text":"Abstract\nBackground and Objectives\nLeiomyoma of uterus forms the most common type of benign tumor of uterus and also the most common pelvic tumor in women. The symptomatology continues to be variable. Surgery has for long been the main mode of therapy for the myomas. For women who wish to retain the uterus for future pregnancies or other reasons, myomectomy is preferred. Recent trend has been toward nonsurgical approaches like GnRH hormone analogs/agonists, RU 486, or selective uterine artery embolization, laparoscopic cryoablation, radiofrequency thermal ablation, and MRGUs. This multicentric study was an attempt to analyze the clinicopathological spectrum in cases of leiomyoma of the uterus at Cheluvamba Hospital, Adichunchanagiri Institute of Medical Sciences, and to know regarding the pattern of presentation, pathological correlation, with type of fibroid, and endometrial and ovarian changes.\nMethods\nA clinical study of 100 cases of fibroid uterus was conducted in the Cheluvamba Hospital, attached to Mysore Medical College and Research Institute, Mysore, and Adichunchanagiri Institute of medical sciences, BG Nagara, Mandya from November 2008 to August 2012. The cases are selected by random allocation. On admission, detailed history, clinical examination, and investigations were recorded.\nResults\nLeiomyoma is the most common benign tumor of the uterus and commonly affects the women of child-bearing age, most commonly in the third decade, 55 %. The most common mode of presentation was menstrual disturbances (76 %), among which menorrhagia was seen in 54 % of the cases. Primary infertility was seen in 15 % of the patients. Intramural fibroids were the most common variety occurring in 60 % of the cases. Endometrial pattern was proliferative in 66.3 %. Cystic ovaries were seen in 8 % of the patients, adenomyosis in 16 % indicating hyperestrogenism.\nConclusion\nFibromyoma (leiomyoma) is the most common benign tumor of the pelvis. It commonly affects the women of child-bearing age, mostly in the third decade and is most commonly seen in multipara. The most common mode of presentation is menstrual disturbances. Intramural fibroid is the most common variety. The proliferative and hyperplastic endometrium was commonly reported. 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J Obstet Gynaecol India. 1993;33:438–9.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nEthics declarations\nConflict of interest\nMaitri Raghavendra Kulkarni, Indranil Dutta, Dilip Kumar Dutta declare that they have no conflicts of interest.\nInformed consent\nAll procedure followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008. Informed consent was obtained from all patients for being included in the study.\nAdditional information\nMaitri Raghavendra Kulkarni is an Assistant Professor in the Adichunchanagiri Institute of Medical Sciences, Mandya, India; Indranil Dutta is an Assistant Professor in the IQ City Medical College, Durgapur, India; Dilip Kumar Dutta is a Consultant in the GICE Hospital, Kalyani, Nadia, India.\nRights and permissions\nAbout this article\nCite this article\nKulkarni, M.R., Dutta, I. & Dutta, D.K. Clinicopathological Study of Uterine Leiomyomas: A Multicentric Study in Rural Population. J Obstet Gynecol India 66 (Suppl 1), 412–416 (2016). https://doi.org/10.1007/s13224-015-0773-y\nReceived:\nAccepted:\nPublished:\nIssue date:\nDOI: https://doi.org/10.1007/s13224-015-0773-y","source_license":"public-domain-us","license_restricted":false}