{"paper_id":"06ca7121-0de2-4772-9b7b-2f00e24f003e","body_text":"ɄɅȱɇȱɑɇȺ ɆȿȾɂɐɂɇȺ\nɆȿȾɂɑɇȱ ɉȿɊɋɉȿɄɌɂȼɂ84\n9. Rebrova OYu. Statisticheskiy analiz meditsinskih \ndannyih. Primenenie paketa prikladnyih programm \nSTATISTICA.M: Media Sfera. 2002;312. \n10. UstInov OV. Psihichne  zdorov’ya yak skladova \nnatsionalnoyi bezpeki. Ukr me d chasopis 1(93). Vidav-\nnitstvo «MORION»; 2013. \n11. Chaban OS. Asteno-nevroticheskiy sindrom. Ru-\nbezhi zdorovya. 2012;1: 16-19. \n12. Yureva LN. Istoriya. Kultura. Psihicheskie i \npovedencheskie rasstroystva. K: Sfera. 2002;224. \n13. Yureva LN. Krizisnyie sosto yaniya. Dnepropet-\nrovsk: Art–Press. 1998;164. \n14. Yureva LN. Professional noe vyigoranie u medi-\ntsinskih rabotnikov: form irovanie, profilaktika i kor-\nrektsiya. K: Sfera. 2004;272. \nɍȾɄ 618.14-089.844 \nȼ.Ɉ. ɉɨɬɚɩɨɜ,\nɘ.ȼ. Ⱦɨɧɫɶɤɚ,\nȱ.ȼ. ȱɜɚɯ,\nɇ.Ƚ. Ƚɚɥɢɰɶɤɚ,\nɆ.ȼ. Ɇɟɞɜɟɞɽɜ\nȿȿɉɉȱȱȾȾȿȿɆɆȱȱɈɈɅɅɈɈȽȽȱȱɑɑɇɇȱȱɈɈɋɋɈɈȻȻɅɅɂɂȼȼɈɈɋɋɌɌȱȱ\nɉɉɈɈȯȯȾȾɇɇȺȺɇɇɂɂɏɏȽȽȱȱɉɉȿȿɊɊɉɉɊɊɈɈɅɅȱȱɎɎȿȿɊɊȺȺɌɌɂɂȼȼɇɇɂɂɏɏ\nɉɉɊɊɈɈɐɐȿȿɋɋȱȱȼȼɀɀȱȱɇɇɈɈɑɑɈɈȲȲɊɊȿȿɉɉɊɊɈɈȾȾɍɍɄɄɌɌɂɂȼȼɇɇɈɈȲȲ\nɋɋɂɂɋɋɌɌȿȿɆɆɂɂ\nȾɁ «Ⱦɧɿɩɪɨɩɟɬɪɨɜɫɶɤɚ ɦɟɞɢɱɧɚ ɚɤɚɞɟɦɿɹ ɆɈɁ ɍɤɪɚʀɧɢ»\nɤɚɮɟɞɪɚ ɚɤɭɲɟɪɫɬɜɚ ɿ ɝɿɧɟɤɨɥɨɝɿʀ\n(ɡɚɜ. – ɞ.ɦɟɞ.ɧ., ɩɪɨɮ. ȼ.Ɉ. ɉɨɬɚɩɨɜ)\nȾɧɿɩɪɨɩɟɬɪɨɜɫɶɤ, 49044, ɍɤɪɚʀɧɚ\nSE \"Dnipropetrovsk medical academy Ministry of Health of Ukraine\" \nobstetrics and gynecology department \nDnipropetrovsk, 49044, Ukraine \ne-mail: medvedev.mv@gmail.com \nɄɥɸɱɨɜɿ ɫɥɨɜɚ: ɥɟɣɨɦɿɨɦɚ ɦɚɬɤɢ, ɝɿɩɟɪɩɥɚɡɿɹ ɟɧɞɨɦɟɬɪɿɹ, ɟɧɞɨɦɟɬɪɿɨɡ, ɮɚɤɬɨɪɢ ɪɢɡɢɤɭ, ɟɩɿɞɟɦɿɨɥɨɝɿɱɧɿ\nɨɫɨɛɥɢɜɨɫɬɿ\nKey words: uterine leiomyoma, endometrial hyperplasia, endometriosis, risk factors, epidemiologic features \nɊɟɮɟɪɚɬ. ɗɩɢɞɟɦɢɨɥɨɝɢɱɟɫɤɢɟ ɨɫɨɛɟɧɧɨɫɬɢ ɫɨɱɟɬɚɧɧɵɯ ɝɢɩɟɪɩɪɨɥɢɮɟɪɚɬɢɜɧɵɯ ɩɪɨɰɟɫɫɨɜ ɠɟɧɫɤɨɣ\nɪɟɩɪɨɞɭɤɬɢɜɧɨɣ ɫɢɫɬɟɦɵ. ɉɨɬɚɩɨɜ ȼ.Ⱥ., Ⱦɨɧɫɤɚɹ ɘ.ȼ., ɂɜɚɯ ɂ.ȼ., Ƚɚɥɢɰɤɚɹ ɇ.Ƚ., Ɇɟɞɜɟɞɟɜ Ɇ.ȼ. ȼɢ ɫ ɫ ɥ ɟ-\nɞɨɜɚɧɢɢ ɩɪɢɧɢɦɚɥɨ ɭɱɚɫɬɢɟ 622 ɠɟɧɳɢɧɵ ɪɟɩɪɨɞɭɤɬɢɜɧɨɝɨ ɜɨɡɪɚɫɬɚ ɫ ɬɚɤɢɦɢ ɝɢɩɟɪɩɪɨɥɢɮɟɪɚɬɢɜɧɵɦɢ\nɩɪɨɰɟɫɫɚɦɢ ɨɪɝɚɧɨɜ ɦɚɥɨɝɨ ɬɚɡɚ, ɤɚɤ ɥɟɣɨɦɢɨɦɚ ɦɚɬɤɢ, ɝɢɩɟɪɩɥɚɡɢɹ ɷɧɞɨɦɟɬɪɢɹ ɢ ɷɧɞɨɦɟɬɪɢɨɡ. ȼ ɯɨɞɟ ɪɚɛɨ-\nɬɵ ɢɡɭɱɟɧɵ ɨɫɧɨɜɧɵɟ ɷɩɢɞɟɦɢɨɥɨɝɢɱɟɫɤɢɟ ɮɚɤɬɨɪɵ, ɩɪɢɫɭɳɢɟ ɭɤɚɡɚɧɧɵɦ ɡɚɛɨɥɟɜɚɧɢɹɦ. ȼɵɹɜɥɟɧɨ, ɱɬɨ ɬɚɤɢɟ\nɡɚɛɨɥɟɜɚɧɢɹ, ɤɚɤ ɥɟɣɨɦɢɨɦɚ ɦɚɬɤɢ, ɷɧɞɨɦɟɬɪɢɨɡ ɢ ɝɢɩɟɪɩɥɚɡɢɹ ɷɧɞɨɦɟɬɪɢɹ ɢɦɟɸɬ ɨɛɳɢɟ ɮɚɤɬɨɪɵ ɪɢɫɤɚ – \nɩɨɜɵɲɟɧɧɚɹ ɦɚɫɫɚ ɬɟɥɚ, ɪɚɧɧɟɟ ɦɟɧɚɪɯɟ, ɩɨɜɵɲɟɧɧɚɹ ɱɚɫɬɨɬɚ ȼɁɈɆɌ, ɚɧɟɦɢɢ, ɝɢɩɟɪɬɨɧɢɱɟɫɤɨɣ ɛɨɥɟɡɧɢ,\nɨɩɟɪɚɬɢɜɧɵɯ ɜɦɟɲɚɬɟɥɶɫɬɜ ɩɨ ɩɨɜɨɞɭ ɝɢɧɟɤɨɥɨɝɢɱɟɫɤɨɣ ɩɚɬɨɥɨɝɢɢ. ȼ ɬɨ ɠɟ ɜɪɟɦɹ ɜɵɹɜɥɟɧɵ ɫɩɟɰɢɮɢɱɟɫɤɢɟ\nɱɟɪɬɵ, ɩɪɢɫɭɳɢɟ ɬɨɥɶɤɨ ɫɨɱɟɬɚɧɢɸ ɥɟɣɨɦɢɨɦɵ ɦɚɬɤɢ ɢ ɝɢɩɟɪɩɥɚɡɢɢ ɷɧɞɨɦɟɬɪɢɹ – ɩɨɜɵɲɟɧɢɟ ɱɚɫɬɨɬɵ\nɋɉɄə ɢ ɫɚɯɚɪɧɨɝɨ ɞɢɚɛɟɬɚ ɜɬɨɪɨɝɨ ɬɢɩɚ, ɚ ɬɚɤɠɟ ɞɥɹ ɥɟɣɨɦɢɨɦɵ ɦɚɬɤɢ ɢ ɷɧɞɨɦɟɬɪɢɨɡɚ – ɫɨɤɪɚɳɟɧɢɟ ɩɪɨ-\nɞɨɥɠɢɬɟɥɶɧɨɫɬɢ ɦɟɧɫɬɪɭɚɥɶɧɨɝɨ ɰɢɤɥɚ, ɩɨɜɵɲɟɧɢɟ ɱɚɫɬɨɬɵ ɛɟɫɩɥɨɞɢɹ.\nAbstract. Epidemiologic peculiarities of combined hyperproliph erative processes of female reproductive system. \nPotapov V.O., Donska Yu.V., Ivach I.V., Halytska V.H., Medvedyev M.V. The study involved 622 women of \nreproductive age with such hyperproliferative pro cesses of the pelvic organs as  uterine leiomyoma, endometrial \nhyperplasia and endometriosis. We studied main epidemiological factors inherent in these diseases. We have found that \nsuch diseases as uterine leiomyoma, endometriosis and endometrial hyp erplasia have common  risk factors: obesity, \nearly menarche, increased frequency of  PID, anemia, hypertension, surgical interventions for gynecological pathology. \nAt the same time, specific features unique to the combination of uterine leiomyoma and endometrial hyperplasia were \nfound: increased frequency of PCOS and type 2 diabetes, as well as for endometriosis and uterine leiomyoma – \nreduction of menstrual cycle length, increase of infertility frequency. \n\n8513/ Ɍɨɦ XVIII / 2\nɅɟɣɨɦɿɨɦɚ ɦɚɬɤɢ ( ɅɆ) ɽ ɩɨɲɢɪɟɧɨɸ ɩɭɯɥɢ-\nɧɨɸ ɠɿɧɨɱɢɯ ɫɬɚɬɟɜɢɯ ɨɪɝɚɧɿɜ, ɱɚɫɬɨɬɚ ɹɤɨʀ ɭ\nɠɿɧɨɤ ɪɟɩɪɨɞɭɤɬɢɜɧɨɝɨ ɜɿɤɭ ɫɬɚɧɨɜɢɬɶ 20-45%. ɍ\nɤɨɠɧɨʀ ɞɪɭɝɨʀ ɯɜɨɪɨʀ ɡ ɅɆ ɫɩɨɫɬɟɪɿɝɚɸɬɶɫɹ ɝɿ-\nɩɟɪɩɥɚɫɬɢɱɧɿ ɩɪɨɰɟɫɢ ɟɧɞɨɦɟɬɪɿɹ ( Ƚȿ), ɩɪɢ-\nɛɥɢɡɧɨ ɭ 15-20% ɬɚɤɢɯ ɠɿɧɨɤ ɜɢɹɜɥɹɽɬɶɫɹ ɝɟɧɿ-\nɬɚɥɶɧɢɣ ɟɧɞɨɦɟɬɪɿɨɡ [2]. \nɇɚɹɜɧɿɫɬɶ ɩɨɽɞɧɚɧɢɯ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɯ\nɩɪɨɰɟɫɿɜ ɜɧɭɬɪɿɲɧɿɯ ɫɬɚɬɟɜɢɯ ɨɪɝɚɧɿɜ ɭ ɠɿɧɨɤ\nɫɭɬɬɽɜɨ ɜɩɥɢɜɚɽ ɧɚ ɤɥɿɧɿɱɧɢɣɩɟɪɟɛɿɝ, ɪɟɩɪɨɞɭɤ-\nɬɢɜɧɭ ɮɭɧɤɰɿɸ, ɟɮɟɤɬɢɜɧɿɫɬɶ ɥɿɤɭɜɚɧɧɹ, ɳɨ ɞɢɤ-\nɬɭɽ ɧɟɨɛɯɿɞɧɿɫɬɶ ɩɨɲɭɤɭ ɧɨɜɢɯ ɫɬɪɚɬɟɝɿɣ ɞɢɮɟ-\nɪɟɧɰɿɣɨɜɚɧɨɝɨ ɩɿɞɯɨɞɭ ɞɨ ɥɿɤɭɜɚɧɧɹ ɰɢɯ ɡɚɯɜɨ-\nɪɸɜɚɧɶ [1]. \nɆɟɬɨɸ ɞɨɫɥɿɞɠɟɧɧɹ ɛɭɥɨ ɜɢɹɜɥɟɧɧɹ ɟɩɿɞɟ-\nɦɿɨɥɨɝɿɱɧɢɯ ɨɫɨɛɥɢɜɨɫɬɟɣ ɩɨɽɞɧɚɧɢɯ ɝɨɪɦɨɧɨ-\nɡɚɥɟɠɧɢɯ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɯ ɡɚɯɜɨɪɸɜɚɧɶ\nɠɿɧɨɱɨʀ ɪɟɩɪɨɞɭɤɬɢɜɧɨʀ ɫɢɫɬɟɦɢ.\nɆȺɌȿɊȱȺɅɂ ɌȺ ɆȿɌɈȾɂ ȾɈɋɅȱȾɀȿɇɖ\nɍ ɞɨɫɥɿɞɠɟɧɧɿ ɛɪɚɥɢ ɭɱɚɫɬɶ 542 ɠɿɧɤɢ ɪɟɩɪɨ-\nɞɭɤɬɢɜɧɨɝɨ ɜɿɤɭ ɡ ɅɆ, ɹɤɚ ɩɿɞɥɹɝɚɥɚ ɨɩɟɪɚ-\nɬɢɜɧɨɦɭ ɥɿɤɭɜɚɧɧɸ, ɬɚ 80 ɡɞɨɪɨɜɢɯ ɠɿɧɨɤ, ɹɤɿ\nɫɤɥɚɥɢ ɤɨɧɬɪɨɥɶɧɭ ɝɪɭɩɭ ( ɄȽ). Ⱦɨɫɥɿɞɠɟɧɧɹ\nɩɪɨɜɨɞɢɥɨɫɶ ɡ 2007 ɩɨ 2013 ɪɿɤ ɧɚ ɛɚɡɿ Ⱦɧɿ-\nɩɪɨɩɟɬɪɨɜɫɶɤɨʀ ɨɛɥɚɫɧɨʀ ɤɥɿɧɿɱɧɨʀ ɥɿɤɚɪɧɿ ɿɦ.\nȱ.ȱ. Ɇɟɱɧɢɤɨɜɚ, Ⱦɧɿɩɪɨɩɟɬɪɨɜɫɶɤɨʀ ɦɿɫɶɤɨʀ ɤɥɿ-\nɧɿɱɧɨʀ ɥɿɤɚɪɧɿ ʋ9 ɬɚ ɩɪɢɜɚɬɧɨʀ ɤɥɿɧɿɤɢ «Ƚɚɪɜɿɫ».\nɁɚɥɟɠɧɨ ɜɿɞɧɚɹɜɧɨɫɬɿ ɥɟɣɨɦɿɨɦɢ ɦɚɬɤɢ ɬɚ ɿɧ-\nɲɢɯ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɯ ɩɪɨɰɟɫɿɜ ɠɿɧɨɱɨʀ\nɪɟɩɪɨɞɭɤɬɢɜɧɨʀ ɫɢɫɬɟɦɢ ɜɫɿ ɠɿɧɤɢ ɛɭɥɢ ɪɨɡɩɨ-\nɞɿɥɟɧɿ ɧɚ 3 ɝɪɭɩɢ: ɝɪɭɩɭ ȱ ɫɤɥɚɥɢ 187 ɠɿɧɨɤ ɡ ɅɆ;\nɞɨ ɝɪɭɩɢ ȱȱ ɭɜɿɣɲɥɢ 176 ɠɿɧɨɤ ɡ ɩɨɽɞɧɚɧɧɹɦ Ƚȿ\nɬɚ ɅɆ; ɝɪɭɩɭ ȱȱȱ ɫɤɥɚɥɢ 179 ɠɿɧɨɤ ɡ ɧɚɹɜɧɿɫɬɸ\nɅɆ ɬɚ ɟɧɞɨɦɟɬɪɿɨɡɭ.\nɁ ɦɟɬɨɸ ɩɿɞɜɢɳɟɧɧɹ ɪɟɩɪɟɡɟɧɬɚɬɢɜɧɨɫɬɿ ɞɚ-\nɧɢɯ ɡ ɞɨɫɥɿɞɠɟɧɧɹ ɛɭɥɢ ɜɢɤɥɸɱɟɧɿ ɜɢɩɚɞɤɢ ɿɧ-\nɮɿɥɶɬɪɚɬɢɜɧɨɝɨ ɟɧɞɨɦɟɬɪɿɨɡɭ, ɩɿɞɨɡɪɢ ɧɚ ɦɚɥɿɝ-\nɧɿɡɚɰɿɸ, ɚɬɢɩɨɜɨʀ ɝɿɩɟɪɩɥɚɡɿʀ ɟɧɞɨɦɟɬɪɿɹ ɬɚ ɬɹɠ-\nɤɨʀ ɟɤɫɬɪɚɝɟɧɿɬɚɥɶɧɨʀ ɩɚɬɨɥɨɝɿʀ.\nɍ ɯɨɞɿ ɪɨɛɨɬɢ ɜɢɜɱɟɧɨ ɚɧɚɦɧɟɫɬɢɱɧɿ ɞɚɧɿ, ɳɨ\nɜɤɥɸɱɚɥɢ: ɨɫɨɛɥɢɜɨɫɬɿ ɩɪɟɦɨɪɛɿɞɧɨɝɨ ɮɨɧɭ,\nɫɩɚɞɤɨɜɭ ɫɯɢɥɶɧɿɫɬɶ, ɩɟɪɟɧɟɫɟɧɿ ɣ ɫɭɩɭɬɧɿ ɟɤɫ-\nɬɪɚɝɟɧɿɬɚɥɶɧɿ ɬɚ ɝɿɧɟɤɨɥɨɝɿɱɧɿ ɡɚɯɜɨɪɸɜɚɧɧɹ,\nɩɟɪɟɧɟɫɟɧɿ ɨɩɟɪɚɬɢɜɧɿ ɝɿɧɟɤɨɥɨɝɿɱɧɿ ɬɚ ɿɧɲɿ ɜɬɪɭ-\nɱɚɧɧɹ. Ɉɫɨɛɥɢɜɚ ɭɜɚɝɚ ɩɪɢɞɿɥɹɥɚɫɹ ɜɢɜɱɟɧɧɸ\nɫɩɟɰɢɮɿɱɧɢɯ ɮɭɧɤɰɿɣ ɠɿɧɨɱɨɝɨ ɨɪɝɚɧɿɡɦɭ: ɦɟɧ-\nɫɬɪɭɚɥɶɧɨʀ, ɫɬɚɬɟɜɨʀ ɬɚ ɪɟɩɪɨɞɭɤɬɢɜɧɨʀ.\nȼɫɿɦ ɠɿɧɤɚɦ ɛɭɥɚ ɜɢɤɨɧɚɧɚ ɦɿɨɦɟɤɬɨɦɿɹ ɥɚ-\nɩɚɪɨɬɨɦɧɢɦ ɚɛɨ ɥɚɩɚɪɨɫɤɨɩɿɱɧɢɦ ɞɨɫɬɭɩɨɦ. Ɂ\nɦɟɬɨɸ ɩɿɞɬɜɟɪɞɠɟɧɧɹ ɞɿɚɝɧɨɡɭ ɩɪɨɜɨɞɢɥɨɫɶ ɦɨɪ-\nɮɨɥɨɝɿɱɧɟ ɞɨɫɥɿɞɠɟɧɧɹ ɜɢɞɚɥɟɧɢɯ ɩɿɞ ɱɚɫ ɯɿɪɭɪ-\nɝɿɱɧɨɝɨ ɜɬɪɭɱɚɧɧɹ ɦɿɨɦɚɬɨɡɧɢɯ ɜɭɡɥɿɜ ɬɚ ɟɧɞɨ-\nɦɟɬɪɿɨʀɞɧɢɯ ɟɤɫɩɥɚɧɬɿɜ. ɉɟɪɟɞ ɩɥɚɧɨɜɢɦ ɨɩɟɪɚ-\nɬɢɜɧɢɦ ɥɿɤɭɜɚɧɧɹɦ ɩɪɨɜɨɞɢɥɨɫɶ ɝɿɫɬɨɥɨɝɿɱɧɟ\nɞɨɫɥɿɞɠɟɧɧɹ ɡɪɚɡɤɿɜ ɟɧɞɨɦɟɬɪɿɹ, ɳɨɛɭɥɢ ɨɬɪɢ-\nɦɚɧɿ ɩɿɞ ɱɚɫ ɞɿɚɝɧɨɫɬɢɱɧɨɝɨ ɜɢɲɤɪɿɛɚɧɧɹ ɚɛɨ\nɚɫɩɿɪɚɰɿɣɧɨʀ ɛɿɨɩɫɿʀ ɟɧɞɨɦɟɬɪɿɹ.\nȾɥɹ ɦɨɪɮɨɥɨɝɿɱɧɨɝɨ ɞɨɫɥɿɞɠɟɧɧɹ ɡ ɤɨɠɧɨɝɨ\nɛɥɨɤɭ ɩɪɨɜɨɞɢɥɢ ɧɟ ɦɟɧɲɟ ɧɿɠ 10 ɡɪɿɡɿɜ. ɉɚ-\nɪɚɮɿɧɨɜɿ ɡɪɿɡɢ ɬɨɜɳɢɧɨɸ 4-5 ɦɤɦ, ɨɬɪɢɦɚɧɿ ɧɚ\nɦɿɤɪɨɬɨɦɿ Microm HM-340, ɛɭɥɢ ɞɟɩɚɪɚɮɿɧɨɜɚɧɿ\nɣ ɩɨɮɚɪɛɨɜɚɧɿ ɝɟɦɚɬɨɤɫɢɥɿɧɨɦ-ɟɨɡɢɧɨɦ. ɋɜɿɬ-\nɥɨɜɚ ɦɿɤɪɨɫɤɨɩɿɹ ɩɪɨɜɨɞɢɥɚɫɶ ɡɚ ɞɨɩɨɦɨɝɨɸ\nɫɜɿɬɥɨɜɨɝɨ ɦɿɤɪɨɫɤɨɩɭ Le ɿca DMLS ɡ ɜɢɤɨɪɢɫ-\nɬɚɧɧɹɦ ɨɛ’ɽɤɬɢɜɿɜ ×10, ×20, ×40, ×100. \nɈɬɪɢɦɚɧɿɞɚɧɿ ɨɛɪɨɛɥɹɥɢ ɡ ɜɢɤɨɪɢɫɬɚɧɧɹɦ\nȿɈɆ ɡɚ ɞɨɩɨɦɨɝɨɸ ɥɿɰɟɧɡɿɣɧɨʀ ɩɪɨɝɪɚɦɢ\nStatistica ( ɜɟɪɫɿɹ 6.1, Statsoft, ɋɒȺ). ɇɨɪɦɚɥɶ-\nɧɿɫɬɶ ɪɨɡɩɨɞɿɥɭ ɨɰɿɧɸɜɚɥɢ ɡɚ ɞɨɩɨɦɨɝɨɸ ɤɪɢ-\nɬɟɪɿʀɜ ɒɚɩɿɪɨ-ɍʀɥɤɚ ɬɚ Ʉɨɥɦɨɝɨɪɨɜɚ. ɍ ɞɨɫɥɿɞ-\nɠɟɧɧɿ ɛɭɥɨ ɩɪɢɣɧɹɬɨ ɪɿɜɟɧɶ ɫɬɚɬɢɫɬɢɱɧɨʀ ɡɧɚ-\nɱɭɳɨɫɬɿ p<0,05. \nɊȿɁɍɅɖɌȺɌɂ ɌȺ Ȳɏ ɈȻȽɈȼɈɊȿɇɇə\nȺɧɚɥɿɡ ɨɬɪɢɦɚɧɢɯ ɞɚɧɢɯ ɩɨɤɚɡɚɜ, ɳɨ ɩɟ-\nɪɟɜɚɠɧɚ ɛɿɥɶɲɿɫɬɶ ɠɿɧɨɤ ɛɭɥɢ ɜɿɤɨɦ ɜɿɞ 26 ɞɨ 40 \nɪɨɤɿɜ. ɋɟɪɟɞɧɿɣ ɜɿɤ ɠɿɧɨɤ, ɳɨ ɭɜɿɣɲɥɢ ɭ ɞɨɫɥɿɞ-\nɠɟɧɧɹ, ɫɬɚɧɨɜɢɜ 32,8 ± 0,85 ɪɨɤɭ. Ƚɪɭɩɢ, ɳɨ\nɞɨɫɥɿɞɠɭɜɚɥɢɫɶ, ɧɟ ɜɿɞɪɿɡɧɹɥɢɫɹ ɜɿɪɨɝɿɞɧɨ ɡɚ\nɜɿɤɨɦ: ɭɄ Ƚɛ ɭ ɜ 32 ± 0,97 ɪɨɤɭ; ɭ ɝɪɭɩɿ ȱ – \n33,5 ± 1,3 ɪɨɤɭ; ɭ ɝɪɭɩɿ ȱȱ – 34,3 + 0,84 ɪɨɤɭ ɬɚ ɭ\nɝɪɭɩɿ ȱȱȱ – 31,4 ± 1,4 ɪɨɤɭ (p>0,05). \nɋɟɪɟɞɧɿɣ ɿɧɞɟɤɫ ɦɚɫɢ ɬɿɥɚ (ȱɆɌ) ɛɭɜ ɜɿɪɨɝɿɞɧɨ\nɜɢɳɢɦ ɭ ɠɿɧɨɤ ɝɪɭɩɢ ȱȱȱ ɩɨɪɿɜɧɹɧɨ ɡ ɄȽ (ɬɚɛɥ.1), \nɳɨ, ɨɱɟɜɢɞɧɨ, ɩɨɜ’ɹɡɚɧɨ ɡ ɛɿɥɶɲ ɱɚɫɬɢɦ ɡɚɫɬɨ-\nɫɭɜɚɧɧɹ ɝɨɪɦɨɧɚɥɶɧɨʀ ɬɟɪɚɩɿʀ ɭ ɠɿɧɨɤ ɡ ɅɆ ɬɚ\nɟɧɞɨɦɟɬɪɿɨɡɨɦ, ɚ ɬɚɤɨɠ ɩɿɞɜɢɳɟɧɧɹɦ ɤɨɧɰɟɧ-\nɬɪɚɰɿʀ ɟɫɬɪɨɝɟɧɿɜ ɡɚ ɪɚɯɭɧɨɤ ɚɪɨɦɚɬɢɡɚɰɿʀ ɚɧɞɪɨ-\nɝɟɧɿɜ ɜ ɠɢɪɨɜɿɣ ɬɤɚɧɢɧɿ.\nɀɿɧɤɢ ɡ ɧɚɞɦɿɪɧɨ ɧɢɡɶɤɨɸ ɦɚɫɨɸ ɬɿɥɚ\n(ȱɆɌ ” 18,5 ɤɝ/ɦ\n2) ɬɚ ɨɠɢɪɿɧɧɹɦ 2 ɫɬɭɩɟɧɹ ɬɚ\nɜɢɳɟ ( ȱɆɌ • 35 ɤɝ/ɦ2) ɜɢɥɭɱɚɥɢɫɹ ɿɡ ɞɨɫɥɿɞ-\nɠɟɧɧɹ, ɜɪɚɯɨɜɭɸɱɢ ɜɟɥɢɤɢɣ ɜɩɥɢɜ ɧɚɞɦɿɪɧɨʀ ɬɚ\nɧɟɞɨɫɬɚɬɧɶɨʀ ɤɿɥɶɤɨɫɬɿ ɠɢɪɨɜɨʀ ɬɤɚɧɢɧɢ ɧɚ\nɝɨɪɦɨɧɚɥɶɧɢɣ ɮɨɧ ɬɚ ɩɪɨɝɪɟɫɭɜɚɧɧɹ ɅɆ, ɱɚɫɬɨɬɭ\nʀʀ ɪɟɰɢɞɢɜɿɜ.\nɈɱɿɤɭɜɚɧɨ ɠɿɧɤɢ ɨɫɧɨɜɧɢɯ ɝɪɭɩ ɯɚɪɚɤɬɟɪɢ-\nɡɭɜɚɥɢɫɶ ɛɿɥɶɲ ɪɚɧɧɿɦ ɫɟɪɟɞɧɿɦ ɜɿɤɨɦ ɦɟɧɚɪɯɟ\nɩɨɪɿɜɧɹɧɨ ɡ ɄȽ (p<0,05), ɳɨ ɜɤɚɡɭɽ ɧɚ ɛɿɥɶɲɭ\nɟɤɫɩɨɡɢɰɿɸ ɞɨ ɟɫɬɪɨɝɟɧɿɜ ɬɚ ɛɿɥɶɲɭ ɤɿɥɶɤɿɫɬɶ\nɦɟɧɫɬɪɭɚɥɶɧɢɯ ɰɢɤɥɿɜ ( Ɇɐ), ɹɤɿɩɿɞɜɢɳɭɸɬɶ\nɿɦɨɜɿɪɧɿɫɬɶ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɯ ɡɚɯɜɨɪɸɜɚɧɶ,\nɳɨ ɜɢɜɱɚɥɢɫɹ. ɋɟɪɟɞɧɹ ɬɪɢɜɚɥɿɫɬɶ Ɇɐ ɧɟ ɜɿɞ-\nɪɿɡɧɹɥɚɫɹ ɜɿɞ ɡɞɨɪɨɜɢɯ ɠɿɧɨɤ ɭ ɜɫɿɯ ɝɪɭɩɚɯ ɨɤɪɿɦ\nȱȱȱ, ɞɟ ɬɪɢɜɚɥɿɫɬɶ Ɇɐ ɛɭɥɚ ɫɬɚɬɢɫɬɢɱɧɨ ɡɧɚɱɭɳɨ\nɦɟɧɲɨɸ, ɧɿɠ ɭ ɪɟɲɬɿ ɝɪɭɩ (p<0,05). \nɉɪɢ ɨɰɿɧɰɿ ɪɨɡɩɨɜɫɸɞɠɟɧɨɫɬɿ ɡɚɩɚɥɶɧɢɯ ɡɚɯ-\nɜɨɪɸɜɚɧɶ ɜɧɭɬɪɿɲɧɿɯ ɝɟɧɿɬɚɥɿɣ ( ɁɁɈɆɌ) ɛɭɥɨ\nɜɢɹɜɥɟɧɨ, ɳɨ ɁɁɈɆɌ ɛɭɥɢ ɱɚɫɬɿɲɟ ɡɚɮɿɤɫɨɜɚɧɿ ɜ\nɨɫɧɨɜɧɢɯ ɝɪɭɩɚɯ ɡ ɧɚɣɛɿɥɶɲɨɸ ɱɚɫɬɨɬɨɸ ɜ ɝɪɭɩɿ\nȱȱȱ. ɇɚ ɧɚɲɭ ɞɭɦɤɭ, ɩɪɢɧɚɣɦɧɿ ɭ ɱɚɫɬɢɧɿ\n\nɄɅȱɇȱɑɇȺ ɆȿȾɂɐɂɇȺ\nɆȿȾɂɑɇȱ ɉȿɊɋɉȿɄɌɂȼɂ86\nɜɢɩɚɞɤɿɜ, ɭ ɠɿɧɨɤ ɰɿɽʀ ɝɪɭɩɢ ɡɚ ɫɢɦɩɬɨɦɢ ɁɁɈɆɌ\nɛɭɥɢ ɩɨɦɢɥɤɨɜɨ ɩɪɢɣɧɹɬɿ ɫɢɦɩɬɨɦɢ ɟɧɞɨɦɟɬ-\nɪɿɨʀɞɧɨʀ ɯɜɨɪɨɛɢ.\nɊɨɡɩɨɜɫɸɞɠɟɧɿɫɬɶ ɫɢɧɞɪɨɦɭ ɩɨɥɿɤɿɫɬɨɡɧɢɯ\nɹɽɱɧɢɤɿɜ (ɋɉɄə) ɛɭɥɚ ɧɚ ɪɿɜɧɿ ɡɞɨɪɨɜɢɯ ɠɿɧɨɤ ɭ\nɜɫɿɯ ɨɫɧɨɜɧɢɯ ɝɪɭɩɚɯ, ɨɤɪɿɦ ɝɪɭɩɢ ȱȱ, ɞɟ ɋɉɄə\nɛɭɜ ɜɢɹɜɥɟɧɢɣ ɜɿɪɨɝɿɞɧɨ ɱɚɫɬɿɲɟ, ɧɿɠ ɭ ɪɟɲɬɿ\nɝɪɭɩ (p<0,05). ɐɟ ɜɤɚɡɭɽ ɧɚ ɩɟɜɧɭ ɪɨɥɶ ɋɉɄə ɜ\nɝɟɧɟɡɿ Ƚȿ ɭ ɱɚɫɬɢɧɢ ɠɿɧɨɤ ɡ ɅɆ, ɨɫɤɿɥɶɤɢ ɜɿɞɨɦɨ,\nɳɨ ɯɚɪɚɤɬɟɪɧɨɸ ɪɢɫɨɸ ɋɉɄə ɽ ɯɪɨɧɿɱɧɚ\nɚɧɨɜɭɥɹɰɿɹ ɡ ɜɿɞɧɨɫɧɨɸ ɝɿɩɟɪɟɫɬɪɨɝɟɧɿɽɸ.\nɉɪɢɦɿɬɧɢɦ ɮɚɤɬɨɦ ɛɭɥɚ ɜ 2 ɪɚɡɢ ɛɿɥɶɲɚ ɱɚɫ-\nɬɨɬɚ ɨɩɟɪɚɬɢɜɧɢɯ ɜɬɪɭɱɚɧɶ ɡ ɩɪɢɜɨɞɭ ɝɿɧɟɤɨ-\nɥɨɝɿɱɧɨʀ ɩɚɬɨɥɨɝɿʀ ɭ ɠɿɧɨɤ ɨɫɧɨɜɧɢɯ ɝɪɭɩ\n(p<0,05). ɐɟ ɳɟ ɪɚɡ ɩɿɞɬɜɟɪɞɠɭɽ ɪɨɥɶ ɦɟɯɚɧɿɱ-\nɧɨɝɨ ɩɨɲɤɨɞɠɟɧɧɹ ɜ ɩɚɬɨɝɟɧɟɡɿ ɅɆ.\nɌɚɛɥɢɰɹ 1 \nɈɫɧɨɜɧɿ ɟɩɿɞɟɦɿɨɥɨɝɿɱɧɿ ɱɢɧɧɢɤɢ, ɯɚɪɚɤɬɟɪɧɿ ɞɥɹ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɯ ɩɪɨɰɟɫɿɜ\nɉɨɤɚɡɧɢɤ ɄȽ\n(n=80) \nȽɪɭɩɚ ȱ\n(n=187) \nȽɪɭɩɚ ȱȱ\n(n=176) \nȽɪɭɩɚ ȱȱȱ\n(n=179) \nȱɆɌ, ɤɝ/ɦ2 (M±m) 23,1±1,3 24,1±0,9 25,4±1,1 26,9±1,1* \nɋɟɪɟɞɧɿɣ ɜɿɤ ɦɟɧɚɪɯɟ, ɪɨɤɢ (M±m) 13,2±0,5§ 11,2±0,4 10,0±0,4 11,1±0,3 \nɋɟɪɟɞɧɹ ɬɪɢɜɚɥɿɫɬɶ Ɇɐ, ɞɧɿ (M±m) 29,1±1,1 28,3±0,8 30,1±1,2 25,2±0,9¥ \nɁɁɈɆɌ, ɚɛɫ.  (%) 5\n(6,3) \n21\n(11,2) \n22\n(12,5) * \n37\n(20,7) * ¥ \nɋɉɄə, ɚɛɫ.  (%) 3\n(3,8) \n4\n(2,1) \n16\n(9,1) § \n6\n(3,4) \nȽɿɧɟɤɨɥɨɝɿɱɧɿ ɨɩɟɪɚɰɿʀ, ɚɛɫ.  (%) 11\n(13,8) § \n48\n(25,7) \n53\n(30,1) \n69\n(38,5) \nȽɿɩɟɪɬɨɧɿɱɧɚ ɯɜɨɪɨɛɚ, ɚɛɫ.  (%) 3\n(3,8) § \n17\n(9,1) \n16\n(9,1) \n21\n(11,7) \nɐɭɤɪɨɜɢɣ ɞɿɚɛɟɬ, ɚɛɫ.  (%) 2\n(2,5) \n7\n(3,7) \n16\n(9,1) § \n8\n(4,5) \nȺɧɟɦɿɹ, ɚɛɫ.  (%) 6\n(7,5) § \n89\n(47,6) \n121\n(68,8) § \n77\n(43,0) \nɉɪɢɦɿɬɤɢ: *  -  ɜɿɞɦɿɧɧɿɫɬɶ ɜɿɪɨɝɿɞɧɚɡɄ Ƚɩ ɪ ɢ p<0,05, § - ɜɿɞɦɿɧɧɿɫɬɶ ɡ ɪɟɲɬɨɸ ɝɪɭɩ ɜɿɪɨɝɿɞɧɚ ɩɪɢ p<0,05, ¥ - ɜɿɞɦɿɧɧɿɫɬɶ ɜɿɪɨɝɿɞɧɚ ɡ\nɝɪɭɩɨɸ ȱȱ ɩɪɢ p<0,05. \nɈɫɧɨɜɧɿ ɝɪɭɩɢ ɯɚɪɚɤɬɟɪɢɡɭɜɚɥɢɫɹ ɛɿɥɶɲɟ ɧɿɠ\nɜ 3 ɪɚɡɢ ɱɚɫɬɢɦ ɜɢɹɜɥɟɧɧɹɦ ɝɿɩɟɪɬɨɧɿɱɧɨʀ ɯɜɨ-\nɪɨɛɢ. ɉɨɹɫɧɟɧɧɹɦ ɬɚɤɨʀ ɟɩɿɞɟɦɿɨɥɨɝɿɱɧɨʀ ɡɧɚɯɿɞ-\nɤɢ ɽ ɩɨɜɿɞɨɦɥɟɧɧɹ ɩɪɨ ɫɩɿɥɶɧɿ ɥɚɧɤɢ ɩɚɬɨɝɟɧɟɡɭ\nɅɆ ɬɚ ɝɿɩɟɪɬɨɧɿɱɧɨʀ ɯɜɨɪɨɛɢ [3]. \nɐɿɤɚɜɢɦ ɫɩɨɫɬɟɪɟɠɟɧɧɹɦ ɽ ɫɬɚɬɢɫɬɢɱɧɨ\nɡɧɚɱɭɳɟ ɩɿɞɜɢɳɟɧɧɹ ɱɚɫɬɨɬɢ ɰɭɤɪɨɜɨɝɨ ɞɿɚɛɟɬɭ ɭ\nɝɪɭɩɿ ȱȱ. ɉɪɢ ɚɧɚɥɿɡɿ ɜɢɩɚɞɤɿɜ ɞɿɚɛɟɬɭ ɫɟɪɟɞ ɠɿɧɨɤ\nɰɿɽʀ ɝɪɭɩɢ ɜɢɹɜɥɟɧɨ, ɳɨ 93,8% ɠɿɧɨɤɡ ɞɿɚɛɟɬɨɦ\nɦɚɥɢ ɣɨɝɨ ɿɧɫɭɥɿɧ-ɧɟɡɚɥɟɠɧɢɣ ɜɚɪɿɚɧɬ, ɹɤɢɣ, ɹɤ ɿ\nɋɉɄə, ɽ ɱɚɫɬɢɧɨɸ ɦɟɬɚɛɨɥɿɱɧɨɝɨ ɫɢɧɞɪɨɦɭ.\nɁɪɨɡɭɦɿɥɨɸ ɛɭɥɚ ɡɧɚɱɧɨ ɩɿɞɜɢɳɟɧɚ ɱɚɫɬɨɬɚ\nɚɧɟɦɿʀ ɫɟɪɟɞ ɠɿɧɨɤ ɡ ɅɆ. ɉɪɢɱɨɦɭ ɧɚɣɛɿɥɶɲ\nɜɢɫɨɤɚ ɱɚɫɬɨɬɚ ɚɧɟɦɿʀ ɛɭɥɚ ɫɟɪɟɞ ɠɿɧɨɤ ɡ ɧɚɣ-\nɛɿɥɶɲ ɜɢɪɚɠɟɧɢɦ ɝɟɦɨɪɚɝɿɱɧɢɦ ɫɢɧɞɪɨɦɨɦ\n(ɝɪɭɩɚ ȱȱ).\nɉɪɢ ɚɧɚɥɿɡɿ ɪɟɩɪɨɞɭɤɬɢɜɧɨʀ ɮɭɧɤɰɿʀ ɭ ɞɨ-\nɫɥɿɞɠɭɜɚɧɢɯ ɝɪɭɩɚɯ ɛɭɥɨ ɜɢɹɜɥɟɧɨ ɩɿɞɜɢɳɟɧɭ\nɱɚɫɬɨɬɭ ɛɟɡɩɥɿɞɞɹ ɫɟɪɟɞ ɠɿɧɨɤ ɡ ɅɆ ( ɬɚɛɥ. 2). \nɈɞɧɚɤ ɫɬɚɬɢɫɬɢɱɧɨ ɡɧɚɱɭɳɟ ɩɿɞɜɢɳɟɧɧɹ ɛɟɡ-\nɩɥɿɞɞɹ ɫɩɨɫɬɟɪɿɝɚɥɨɫɹ ɥɢɲɟ ɭ ɠɿɧɨɤ ɝɪɭɩɢ ȱȱȱ\n(p<0,05), ɳɨ ɫɜɿɞɱɢɬɶ ɩɪɨ ɛɿɥɶɲɢɣ ɜɩɥɢɜ ɧɚ\nɮɟɪɬɢɥɶɧɿɫɬɶ ɟɧɞɨɦɟɬɪɿɨɡɭ ɧɿɠ ɥɟɣɨɦɿɨɦɢ ɦɚɬɤɢ.\nɉɪɢ ɚɧɚɥɿɡɿ ɱɚɫɬɨɬɢ ɚɛɨɪɬɿɜ ɛɭɥɨ ɜɢɹɜɥɟɧɨ ʀʀ\nɩɿɞɜɢɳɟɧɧɹ ɭ ɠɿɧɨɤ ɝɪɭɩɢ ȱ ɬɚ ȱȱ. ȼɿɞɧɨɫɧɨ\nɧɟɜɢɫɨɤɚ ɱɚɫɬɨɬɚ ɚɛɨɪɬɿɜ ɭ ɠɿɧɨɤ ɝɪɭɩɢ ȱȱȱ, ɹɤɚ\nɛɭɥɚ ɚɧɚɥɨɝɿɱɧɚ ɞɚɧɢɦ ɭ ɡɞɨɪɨɜɢɯ ɠɿɧɨɤ, ɩɨ-\nɜ’ɹɡɚɧɚ ɡ ɜɢɫɨɤɨɸ ɱɚɫɬɨɬɨɸ ɛɟɡɩɥɿɞɞɹ ɭ ɰɿɣ\nɝɪɭɩɿ. ȼ ɰɿɥɨɦɭ, ɜɢɫɨɤɚ ɱɚɫɬɨɬɚ ɚɛɨɪɬɿɜ ɽ ɨɞɧɿɽɸ\nɡ ɦɨɠɥɢɜɢɯ ɩɪɢɱɢɧ ɜɢɧɢɤɧɟɧɧɹ ɝɿɩɟɪɩɪɨɥɿɮɟ-\nɪɚɬɢɜɧɢɯ ɩɪɨɰɟɫɿɜ ɜɧɭɬɪɿɲɧɿɯ ɠɿɧɨɱɢɯ ɝɟɧɿɬɚɥɿɣ.\nɉɨɥɨɝɢ ɜ ɚɧɚɦɧɟɡɿ ɡɭɫɬɪɿɱɚɥɢɫɹ ɡ ɨɞɧɚɤɨɜɨɸ\nɱɚɫɬɨɬɨɸ ɭ ɜɫɿɯ ɝɪɭɩɚɯ, ɳɨ ɞɨɫɥɿɞɠɭɜɚɥɢɫɶ,\nɨɤɪɿɦɝɪɭɩɢ ȱȱȱ, ɞɟ ɜɨɧɚ ɛɭɥɚ ɜɿɪɨɝɿɞɧɨ ɧɢɠɱɨɸ\n(p<0,05), ɳɨ ɩɨɜ’ɹɡɚɧɨ ɡɿ ɡɝɚɞɚɧɢɦ ɜɢɳɟ ɮɚɤ-\nɬɨɪɨɦ – ɜɢɫɨɤɨɸ ɪɨɡɩɨɜɫɸɞɠɟɧɿɫɬɸ ɧɟɩɥɿɞɧɨɫɬɿ\nɭ ɠɿɧɨɤ ɡ ɩɨɽɞɧɚɧɧɹɦ ɅɆ ɬɚ ɟɧɞɨɦɟɬɪɿɨɡɭ.\n\n8713/ Ɍɨɦ XVIII / 2\nɌɚɛɥɢɰɹ 2 \nɊɟɩɪɨɞɭɤɬɢɜɧɚ ɮɭɧɤɰɿɹ ɜ ɚɧɚɦɧɟɡɿ\nɉɨɤɚɡɧɢɤ ɄȽ\n(n=80) \nȽɪɭɩɚ ȱ\n(n=187) \nȽɪɭɩɚ ȱȱ\n(n=176) \nȽɪɭɩɚ ȱȱȱ\n(n=179) \nȻɟɡɩɥɿɞɞɹ, ɚɛɫ.  (%) 9\n(11,3) § \n28\n(15,0) \n39\n(22,2) \n89\n(49,7) § \nȺɛɨɪɬɢ, ɚɛɫ.  (%) 35\n(43,8) * ¥ \n117\n(62,6) \n122\n(69,3) \n76\n(42,5) * ¥ \nɉɨɥɨɝɢ, ɚɛɫ.  (%) 66\n(82,5) \n143\n(76,5) \n131\n(74,4) \n97\n(54,2) § \nɉɪɢɦɿɬɤɢ: *  -  ɜɿɞɦɿɧɧɿɫɬɶ ɜɿɪɨɝɿɞɧɚ ɡ ɝɪɭɩɨɸ ȱ ɩɪɢ p<0,05, § - ɜɿɞɦɿɧɧɿɫɬɶ ɡ ɪɟɲɬɨɸ ɝɪɭɩ ɜɿɪɨɝɿɞɧɚ ɩɪɢ p<0,05, ¥ - ɜɿɞɦɿɧɧɿɫɬɶ\nɜɿɪɨɝɿɞɧɚ ɡ ɝɪɭɩɨɸ ȱȱ ɩɪɢ p<0,05. \nȼɂɋɇɈȼɄɂ\n1. Ɍɚɤɢɦ ɱɢɧɨɦ, ɛɭɥɨ ɜɢɹɜɥɟɧɨ ɬɚ ɩɪɨɚɧɚ-\nɥɿɡɨɜɚɧɨ ɨɫɧɨɜɧɿ ɟɩɿɞɟɦɿɨɥɨɝɿɱɧɿ ɨɫɨɛɥɢɜɨɫɬɿ ɭ\nɠɿɧɨɤ ɡ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɦɢ ɡɚɯɜɨɪɸɜɚɧɧɹɦɢ\nɜɧɭɬɪɿɲɧɿɯ ɫɬɚɬɟɜɢɯ ɨɪɝɚɧɿɜ. ȼɢɹɜɥɟɧɨ, ɳɨ ɬɚɤɿ\nɡɚɯɜɨɪɸɜɚɧɧɹ, ɹɤ ɥɟɣɨɦɿɨɦɚ ɦɚɬɤɢ, ɟɧɞɨɦɟɬɪɿɨɡ\nɬɚ ɝɿɩɟɪɩɥɚɡɿɹ ɟɧɞɨɦɟɬɪɿɹ ɦɚɸɬɶ ɫɩɿɥɶɧɿ ɩɚɬɨ-\nɝɟɧɟɬɢɱɧɿ ɥɚɧɤɢ, ɳɨ ɩɪɨɹɜɥɹɽɬɶɫɹ ɭ ɧɚɹɜɧɨɫɬɿ\nɬɚɤɢɯ ɫɩɿɥɶɧɢɯ ɞɥɹ ɰɢɯ ɡɚɯɜɨɪɸɜɚɧɶ ɮɚɤɬɨɪɿɜ\nɪɢɡɢɤɭ, ɹɤ ɩɿɞɜɢɳɟɧɚ ɦɚɫɚ ɬɿɥɚ, ɪɚɧɧɽɦɟɧɚɪɯɟ,\nɩɿɞɜɢɳɟɧɚ ɱɚɫɬɨɬɚ ɁɁɈɆɌ, ɚɧɟɦɿʀ, ɝɿɩɟɪɬɨɧɿɱɧɨʀ\nɯɜɨɪɨɛɢ, ɨɩɟɪɚɬɢɜɧɢɯ ɜɬɪɭɱɚɧɶ ɡ ɩɪɢɜɨɞɭ ɝɿɧɟ-\nɤɨɥɨɝɿɱɧɨʀ ɩɚɬɨɥɨɝɿʀ. Ɋɚɡɨɦ ɡ ɬɢɦ, ɜɢɹɜɥɟɧɿ ɫɩɟ-\nɰɢɮɿɱɧɿ ɪɢɫɢ, ɩɪɢɬɚɦɚɧɧɿ ɬɿɥɶɤɢ ɩɨɽɞɧɚɧɧɸ ɅɆ\nɬɚ Ƚȿ – ɩɿɞɜɢɳɟɧɧɹ ɱɚɫɬɨɬɢ ɋɉɄə ɬɚ ɰɭɤɪɨɜɨɝɨ\nɞɿɚɛɟɬɭ ɞɪɭɝɨɝɨ ɬɢɩɭ, ɚ ɬɚɤɨɠ ɞɥɹ ɅɆ ɬɚ\nɟɧɞɨɦɟɬɪɿɨɡɭ – ɫɤɨɪɨɱɟɧɧɹ ɬɪɢɜɚɥɨɫɬɿ ɦɟɧɫɬɪɭɚ-\nɥɶɧɨɝɨ ɰɢɤɥɭ, ɩɿɞɜɢɳɟɧɧɹ ɱɚɫɬɨɬɢ ɛɟɡɩɥɿɞɞɹ.\n2. Ɉɬɠɟ, ɧɚ ɨɫɧɨɜɿ ɪɟɬɟɥɶɧɨɝɨ ɜɢɜɱɟɧɧɹ\nɚɧɚɦɧɟɫɬɢɱɧɢɯ ɞɚɧɢɯ ɩɚɰɿɽɧɬɤɢ ɡ ɅɆ ɦɨɠɧɚ\nɩɪɨɝɧɨɡɭɜɚɬɢ ɧɚɹɜɧɿɫɬɶ ɩɨɽɞɧɚɧɧɹ ɨɫɬɚɧɧɶɨʀ ɡ\nɬɚɤɢɦɢ ɝɿɩɟɪɩɪɨɥɿɮɟɪɚɬɢɜɧɢɦɢ ɩɪɨɰɟɫɚɦɢ ɹɤ\nɟɧɞɨɦɟɬɪɿɨɡ ɬɚ ɝɿɩɟɪɩɥɚɡɿɹ ɟɧɞɨɦɟɬɪɿɹ, ɚ ɬɚɤɨɠ\nɭɫɩɿɲɧɿɫɬɶ ɥɿɤɭɜɚɧɧɹ ɬɚ ɧɚɫɥɿɞɤɢ ɞɥɹ ɪɟɩɪɨ-\nɞɭɤɬɢɜɧɨʀ ɮɭɧɤɰɿʀ, ɳɨ ɞɨɩɨɦɨɠɟ ɨɛɢɪɚɬɢ ɩɪɚ-\nɜɢɥɶɧɭ ɥɿɤɭɜɚɥɶɧɭ ɫɬɪɚɬɟɝɿɸ ɧɚ ɪɚɧɧɿɯ ɟɬɚɩɚɯ.\nɋɋɉɉɂɂɋɋɈɈɄɄɅɅȱȱɌɌȿȿɊɊȺȺɌɌɍɍɊɊɂɂ\n1. Ɉɬ ɞɢɫɤɪɢɩɚɧɫɚ ɤ ɤɨɦɩɥɚɣɧɫɭ ɜ ɤɨɦɩɥɟɤɫɧɨɦ\nɥɟɱɟɧɢɢ ɛɨɥɶɧɵɯ ɥɟɣɨɦɢɨɦɨɣ ɢ ɷɧɞɨɦɟɬɪɢɨɡɨɦ / \nȼ.ɇ. ɋɟɪɨɜ, Ⱥ.Ʌ. Ɍɢɯɨɦɢɪɨɜ, Ⱦ.Ɇ. Ʌɭɛɧɢɧ, ɂ.Ⱥ. Ʉɚ-\nɡɚɧɰɟɜɚ // Ⱥɤɬɭɚɥɶɧɵɟ ɜɨɩɪɨɫɵ ɤɥɢɧɢɱɟɫɤɨɣ ɠɟɥɟɡɧɨ-\nɞɨɪɨɠɧɨɣ ɦɟɞɢɰɢɧɵ. – 2000. – ʋ 5. – C. 127-132. \n2. Ɍɢɯɨɦɢɪɨɜɚ Ⱥ.Ʌ. Ɇɢɨɦɚ ɦɚɬɤɢ / Ⱥ.Ʌ. Ɍɢɯɨɦɢ-\nɪɨɜ., Ⱦ.Ɇ. Ʌɭɛɧɢɧ – Ɇ.: ɆɂȺ, 2006. — 176 c. \n3. Faerstein E. Risk factors for uterine leiomyoma: a \npractice-based case-control study. II. Atherogenic risk \nfactors and potential sources of uterine irritation / E. Faer-\nstein, M. Szklo, N.B. Rosenshei n // Am. J. Epidemiol. — \n2001. — Vol. 153, N 1. — P. 11-19. \nRREEFFEERREENNCCEESS\n1. Serov VN, Tihomirov AL, Lubnin DM, Kazant-\nseva IA. Ot diskripansa k komplaynsu v kompleksnom \nlechenii bolnyih leyomiomoy i endometriozom. Aktual-\nnyie voprosyi klinicheskoy zheleznodorozhnoy meditsi-\nnyi. 2000;5:127-32. \n2. Tihomirova AL, Lubnin DM. Mioma matki. M: \nMIA. 2006;176. \n3. Faerstein E, Szklo M,  Rosenshein NB. Risk \nfactors for uterine leiomyoma: a practice-based case-\ncontrol study. II Atherogenic risk factors and potential \nsources of uterine irritation. Am J Epidemiol. \n2001;153(1):11-9.","source_license":"CC0","license_restricted":false}