{"paper_id":"011a887e-ff98-45c0-9a78-6f42b952fbab","body_text":"Abstract\nDespite the prevalence of endometriosis in the human population, there is a shortage of animal models for studying it. The authors describe the development of a swine model of endometriosis that allows researchers to evaluate laparoscopic techniques and instruments for diagnosing and treating the condition.\nThis is a preview of subscription content, access via your institution\nAccess options\nSimilar content being viewed by others\nReferences\nCorson, S. Endometriosis: The Enigmatic Disease (Essential Medial Information Systems, Durant, 1992).\nFreeman, L. Veterinary Endosurgery (Mosby, St. Louis, 1999).\nInstitute of Laboratory Animal Resources, National Research Council. Guide for the Care and Use of Laboratory Animals (National Academy Press, Washington, DC, 1996).\nGarbers, D.L. & First, N.L. The effects of injected oestradiol-17-β, progesterone and dietary ICI 33828 on ovarian and pituitary functions in the sow and gilt. J. Reprod. Fertil. 20, 451–464 (1969).\nGooneratne, A., Hartmann, P.E., McCauley, I. & Martin, C.E. Control of parturition in the sow using progesterone and prostaglandin. Aust. J. Biol. Sci. 32, 587–595 (1979).\nPetrucco, O.M. et al. Ablation of endometriotic implants in rabbits by hematoporphy derivative photoradiation therapy using the gold vapor laser. Lasers Surg. Med. 10, 344–348 (1990).\nCummings, A.M. & Metcalf, J.L. Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats. Fundam. Appl. Toxicol. 27, 287–290 (1995).\nD'Hooghe, T.M. et al. Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis). Am. J. Obstet. Gynecol. 173, 125–134 (1995).\nAcknowledgements\nThe authors thank Mary K. Reinhard, DVM, ACVP, ACLAM for the histological evaluation.\nAuthor information\nAuthors and Affiliations\nCorresponding author\nRights and permissions\nAbout this article\nCite this article\nSiegel, J., Kolata, R. Endometriosis Model Development in Swine. Lab Anim 32, 41–45 (2003). https://doi.org/10.1038/laban0403-41\nReceived:\nAccepted:\nIssue date:\nDOI: https://doi.org/10.1038/laban0403-41","source_license":"CC0","license_restricted":false}